ID   T1R2_MYCPN              Reviewed;         115 AA.
AC   P75432;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Putative type I restriction enzyme MpnIIP endonuclease subunit middle part {ECO:0000303|PubMed:12654995, ECO:0000303|PubMed:8948633};
DE            Short=R protein middle part;
GN   OrderedLocusNames=MPN_346; ORFNames=H91_orf115, MP490;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
RN   [2]
RP   NOMENCLATURE.
RX   PubMed=12654995; DOI=10.1093/nar/gkg274;
RA   Roberts R.J., Belfort M., Bestor T., Bhagwat A.S., Bickle T.A.,
RA   Bitinaite J., Blumenthal R.M., Degtyarev S.K., Dryden D.T., Dybvig K.,
RA   Firman K., Gromova E.S., Gumport R.I., Halford S.E., Hattman S.,
RA   Heitman J., Hornby D.P., Janulaitis A., Jeltsch A., Josephsen J., Kiss A.,
RA   Klaenhammer T.R., Kobayashi I., Kong H., Krueger D.H., Lacks S.,
RA   Marinus M.G., Miyahara M., Morgan R.D., Murray N.E., Nagaraja V.,
RA   Piekarowicz A., Pingoud A., Raleigh E., Rao D.N., Reich N., Repin V.E.,
RA   Selker E.U., Shaw P.C., Stein D.C., Stoddard B.L., Szybalski W.,
RA   Trautner T.A., Van Etten J.L., Vitor J.M., Wilson G.G., Xu S.Y.;
RT   "A nomenclature for restriction enzymes, DNA methyltransferases, homing
RT   endonucleases and their genes.";
RL   Nucleic Acids Res. 31:1805-1812(2003).
RN   [3]
RP   DISCUSSION OF SEQUENCE.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=23300489; DOI=10.1371/journal.pgen.1003191;
RA   Lluch-Senar M., Luong K., Llorens-Rico V., Delgado J., Fang G., Spittle K.,
RA   Clark T.A., Schadt E., Turner S.W., Korlach J., Serrano L.;
RT   "Comprehensive methylome characterization of Mycoplasma genitalium and
RT   Mycoplasma pneumoniae at single-base resolution.";
RL   PLoS Genet. 9:e1003191-e1003191(2013).
CC   -!- FUNCTION: The middle section of a putative type I restriction enzyme
CC       that if reconstituted might recognize 5'-GAN(7)TAY-3' and cleave a
CC       random distance away (Probable). Subunit R is required for both
CC       nuclease and ATPase activities, but not for modification
CC       (PubMed:12654995). {ECO:0000303|PubMed:12654995,
CC       ECO:0000305|PubMed:8948633}.
CC   -!- CAUTION: Could be the product of a pseudogene; in this organism the
CC       endonuclease subunit carries 2 frameshift mutations (resulting in 3
CC       short ORFs) and is probably not expressed.
CC       {ECO:0000305|PubMed:23300489, ECO:0000305|PubMed:8948633}.
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DR   EMBL; U00089; AAB96138.1; -; Genomic_DNA.
DR   PIR; S73816; S73816.
DR   RefSeq; NP_110034.1; NC_000912.1.
DR   AlphaFoldDB; P75432; -.
DR   SMR; P75432; -.
DR   IntAct; P75432; 1.
DR   EnsemblBacteria; AAB96138; AAB96138; MPN_346.
DR   KEGG; mpn:MPN_346; -.
DR   PATRIC; fig|272634.6.peg.371; -.
DR   HOGENOM; CLU_2106267_0_0_14; -.
DR   BioCyc; MPNE272634:G1GJ3-546-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..115
FT                   /note="Putative type I restriction enzyme MpnIIP
FT                   endonuclease subunit middle part"
FT                   /id="PRO_0000210663"
SQ   SEQUENCE   115 AA;  13468 MW;  95E6E8BEFE9F054B CRC64;
     MSDALDDENV LCFRYKSYYI KDDGSRIDTL NEERIKHIVD FTLDKYLDAT QNTPKFDNFE
     NPVKEGFNSI FACESKEAAI EYYKEFKKQI EQKKLPIKIA SIIAQTKVVM NKKLV