T214A_ANTAG
ID T214A_ANTAG Reviewed; 1031 AA.
AC Q85B66;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Putative protein TIC 214 N-terminal part {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=ORF1031;
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Anthoceros angustus (Hornwort) (Anthoceros formosae).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Anthocerotophyta;
OC Anthocerotopsida; Anthocerotidae; Anthocerotales; Anthocerotaceae;
OC Anthoceros.
OX NCBI_TaxID=48387;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND RNA EDITING.
RX PubMed=12527781; DOI=10.1093/nar/gkg155;
RA Kugita M., Kaneko A., Yamamoto Y., Takeya Y., Matsumoto T., Yoshinaga K.;
RT "The complete nucleotide sequence of the hornwort (Anthoceros formosae)
RT chloroplast genome: insight into the earliest land plants.";
RL Nucleic Acids Res. 31:716-721(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND RNA EDITING.
RC TISSUE=Thallus;
RX PubMed=12711687; DOI=10.1093/nar/gkg327;
RA Kugita M., Yamamoto Y., Fujikawa T., Matsumoto T., Yoshinaga K.;
RT "RNA editing in hornwort chloroplasts makes more than half the genes
RT functional.";
RL Nucleic Acids Res. 31:2417-2423(2003).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- RNA EDITING: Modified_positions=26 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 36 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 71 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 103 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 130 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 168 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 218 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 348 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 408 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 470 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 537 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 566 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 618 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 672 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 813 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}, 819 {ECO:0000269|PubMed:12527781,
CC ECO:0000269|PubMed:12711687}; Note=The nonsense codons at positions 71,
CC 130, 348, 408, 537 and 813 are modified to sense codons.;
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. In A.formosae this
CC protein is in two parts: ORF 1031 (N-terminal) and ORF 473 (C-
CC terminal).
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DR EMBL; AB086179; BAC55409.1; -; Genomic_DNA.
DR EMBL; AB087492; BAC55509.1; -; mRNA.
DR RefSeq; NP_777472.1; NC_004543.1.
DR AlphaFoldDB; Q85B66; -.
DR SMR; Q85B66; -.
DR GeneID; 2553505; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 2.
DR Pfam; PF05758; Ycf1; 3.
PE 5: Uncertain;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW RNA editing; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1031
FT /note="Putative protein TIC 214 N-terminal part"
FT /id="PRO_0000217295"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1031 AA; 121135 MW; 8D03982D643A0728 CRC64;
MITSITLLFS ILWAQILSWI SISGPLILFG LYYGFSITLP MGPSQILSIR AFLLEGNLSG
LMALGGSTLG QLIILISIFY SPLYIMLLKP HAITLITLPY VLFYWYEIKD LSDYQPLRPI
TSLNDTGIIQ IFLNSFLFQI FNPILLPSPV LTRLVKLFLF RYSHNSFFVI SLFCGWLGGN
ILLINLSKFL LIRIKNNSST LYLLVKRLIY RTFSIIIFVA CLSYLGKFPV PFSMKKSSDE
SSLNEWKAER LSWLYKPWPT SLFNYRKWNR PLRYIENSRF SNKSPVKRNV SQYFFDVCLN
DGRQRISFTS LPSFSIFEKN LKNYLNVSRI SSSSDVFYQE WINTKKEQKD DLYSEVEERI
KALDNGFSLE HAIEKRIGFS SINKEDIPNK TYDPFLDGEF RGKVAVSQSP LLLTGKSYGL
TKTQKLLHLS RKNNKLKFWI SNKWRKLERK DLPLPWEPLT QDARRVLILL IKGLRNKKSK
IDSQRNDFSK EQGVIALNEE NISPEFSAKT NNTNFLREKA IRKSHINWEL VLNLSLRQRI
LYFNYLEKVK WETIKNSWKD LISGNFTEVK NIGSLVMKIM KIHQESPLQE FHKEVPRWTS
KLKNDKFDVI AIGVTDIRQR KVRNLGYLIK GREKRRKIVR RFSQQSDFRR KLIKGSMRAR
RRKTLIWKIL QFKTHSPFFL KITEKPALFR STEIMEDIDV KGTFLNTIGI EKLISLLSER
GVAIKGTKAD RLAIANRWDF PLAQWGRSWL LIIQSYLRKY VVLPILIILK NISRLFLLQV
PEWNEDWNEW SEEIHIKCTY DGTEVSEREL PEQWLRDGLQ IKIIYPFHLK PWHNSKFKEK
GNRNMEPNFP HTQNKGKETS DNKAYRLQKN KKFKYSFLTA WGFQTNLPFG NIKKQPSFWK
PVIKELKKRW KREILSKTAN FYELYYNISL LYRKSDISNR FKIFAEFDIQ TDERMNHEIS
KIQVNSESGG ASVTDDGIKR ESPLGITLNS ENSNFSENED FLWEIPVESR YKTAKNIKKL
ESLVVSKNNL T