ID   T229A_MOUSE             Reviewed;         371 AA.
AC   B9EJI9;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Transmembrane protein 229A;
GN   Name=Tmem229a;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM229 family. {ECO:0000305}.
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DR   EMBL; BC147241; AAI47242.1; -; mRNA.
DR   EMBL; BC147242; AAI47243.1; -; mRNA.
DR   CCDS; CCDS51729.1; -.
DR   RefSeq; NP_795987.2; NM_177013.3.
DR   AlphaFoldDB; B9EJI9; -.
DR   STRING; 10090.ENSMUSP00000116234; -.
DR   iPTMnet; B9EJI9; -.
DR   PhosphoSitePlus; B9EJI9; -.
DR   MaxQB; B9EJI9; -.
DR   PaxDb; B9EJI9; -.
DR   PRIDE; B9EJI9; -.
DR   ProteomicsDB; 254626; -.
DR   Antibodypedia; 55409; 49 antibodies from 11 providers.
DR   Ensembl; ENSMUST00000127247; ENSMUSP00000116234; ENSMUSG00000048022.
DR   GeneID; 319832; -.
DR   KEGG; mmu:319832; -.
DR   UCSC; uc009bcc.1; mouse.
DR   CTD; 730130; -.
DR   MGI; MGI:2442812; Tmem229a.
DR   VEuPathDB; HostDB:ENSMUSG00000048022; -.
DR   eggNOG; ENOG502QUNK; Eukaryota.
DR   GeneTree; ENSGT00390000010899; -.
DR   HOGENOM; CLU_048581_0_0_1; -.
DR   InParanoid; B9EJI9; -.
DR   OMA; FHLVFYP; -.
DR   OrthoDB; 1476201at2759; -.
DR   PhylomeDB; B9EJI9; -.
DR   TreeFam; TF336481; -.
DR   BioGRID-ORCS; 319832; 1 hit in 70 CRISPR screens.
DR   ChiTaRS; Tmem229a; mouse.
DR   PRO; PR:B9EJI9; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; B9EJI9; protein.
DR   Bgee; ENSMUSG00000048022; Expressed in cerebellar nuclear complex and 126 other tissues.
DR   Genevisible; B9EJI9; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..371
FT                   /note="Transmembrane protein 229A"
FT                   /id="PRO_0000391849"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   371 AA;  41526 MW;  AAF56AAD640AFAFA CRC64;
     MAGSDVASEG PSPRDGATRR PGATGGLRSQ AAASCPEPLS AAEAPAERGA LPAWMRLYFY
     GMHGITLDVL VSSARRFARS LDLRMLGFSS PYRCLLHSLT HFALEQLYLQ RPRCPSAFLF
     NFLLYPSAHV GLQTLAGQAL RLSLGGGPGG AAAPALGALD LALQYVLALY HGQVFLKRFL
     CLRYPRRRDQ HTRDTLPAAR DAQILWEAGG QRRGPGGARG TERSPTQGLP DLLRFLFFGM
     HGFLDEIFFT FFFNVLGQGD RASSGHTSLW SFFMYGSCSF VVEKLYFHLH YSRGWGTWKR
     VPIYVIFIYA WEFSWGLGLR MCGACSWDYS HYPLNFMGLI TLMYLPGWLF LSVYQDLLSN
     VLWRVQYVPT N