ID   T22D1_BATSU             Reviewed;         144 AA.
AC   Q27I66;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=TSC22 domain family protein 1;
DE   AltName: Full=Transforming growth factor beta-1-induced transcript 4 protein;
GN   Name=TSC22D1; Synonyms=TGFB1I4;
OS   Bathyergus suillus (Cape dune mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Bathyergus.
OX   NCBI_TaxID=10172;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Head;
RA   Nikitina N.V., Kidson S.H.;
RT   "Eye development in the Cape dune mole rat.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor. Acts on the C-type natriuretic
CC       peptide (CNP) promoter (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer or heterodimer. Can form a heterodimer with TSC22D4
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TSC-22/Dip/Bun family. {ECO:0000305}.
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DR   EMBL; DQ400348; ABD62771.1; -; mRNA.
DR   AlphaFoldDB; Q27I66; -.
DR   SMR; Q27I66; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR000580; TSC-22_Dip_Bun.
DR   Pfam; PF01166; TSC22; 1.
DR   PROSITE; PS01289; TSC22; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..144
FT                   /note="TSC22 domain family protein 1"
FT                   /id="PRO_0000254946"
FT   REGION          77..98
FT                   /note="Leucine-zipper"
FT   REGION          109..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   144 AA;  15650 MW;  1C4EA438562DD364 CRC64;
     MKAQWCRPVA MDLGVYQLRH FSISFLSSLL GTENASVRLD NSSSGASVVA IDNKIEQAMD
     LVKSHLMYAV REEVEVLKEQ IKELIEKNSQ LEQENNLLKT LASPEQLAQF QAQLQTGSPP
     ATTQPQGSTQ PPAQPASQGS GPTA