ID   T22D1_BOVIN             Reviewed;         144 AA.
AC   Q3MHL6;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=TSC22 domain family protein 1;
GN   Name=TSC22D1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcriptional repressor. Acts on the C-type natriuretic
CC       peptide (CNP) promoter (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer or heterodimer. Can form a heterodimer with TSC22D4
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TSC-22/Dip/Bun family. {ECO:0000305}.
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DR   EMBL; BC105192; AAI05193.1; -; mRNA.
DR   RefSeq; NP_001029549.1; NM_001034377.1.
DR   AlphaFoldDB; Q3MHL6; -.
DR   SMR; Q3MHL6; -.
DR   STRING; 9913.ENSBTAP00000025431; -.
DR   PaxDb; Q3MHL6; -.
DR   PRIDE; Q3MHL6; -.
DR   Ensembl; ENSBTAT00000025431; ENSBTAP00000025431; ENSBTAG00000047739.
DR   GeneID; 510359; -.
DR   KEGG; bta:510359; -.
DR   CTD; 8848; -.
DR   VEuPathDB; HostDB:ENSBTAG00000047739; -.
DR   eggNOG; KOG4797; Eukaryota.
DR   GeneTree; ENSGT00940000163647; -.
DR   HOGENOM; CLU_148757_0_0_1; -.
DR   InParanoid; Q3MHL6; -.
DR   OMA; MKAQWCR; -.
DR   OrthoDB; 1602203at2759; -.
DR   TreeFam; TF329224; -.
DR   Proteomes; UP000009136; Chromosome 12.
DR   Bgee; ENSBTAG00000047739; Expressed in myometrium and 104 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR000580; TSC-22_Dip_Bun.
DR   Pfam; PF01166; TSC22; 1.
DR   PROSITE; PS01289; TSC22; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..144
FT                   /note="TSC22 domain family protein 1"
FT                   /id="PRO_0000285808"
FT   REGION          77..98
FT                   /note="Leucine-zipper"
FT   REGION          109..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   144 AA;  15680 MW;  B8AEF42657C50892 CRC64;
     MKSQWCRPVA MDLGVYQLRH FSISFLSSLL GTENASVRLD NSSSGASVVA IDNKIEQAMD
     LVKSHLMYAV REEVEVLKEQ IKELIEKNSQ LEQENNLLKT LASPEQLAQF QAQLQTGSPP
     ATTQPQGTTQ PPAQPASQGS GPTA