ID   T238L_HUMAN             Reviewed;          79 AA.
AC   A6NJY4; A0A1B0GVL6;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-APR-2021, sequence version 3.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Transmembrane protein 238-like {ECO:0000305};
GN   Name=TMEM238L {ECO:0000312|HGNC:HGNC:44356};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16344560; DOI=10.1101/gr.4039406;
RA   Kimura K., Wakamatsu A., Suzuki Y., Ota T., Nishikawa T., Yamashita R.,
RA   Yamamoto J., Sekine M., Tsuritani K., Wakaguri H., Ishii S., Sugiyama T.,
RA   Saito K., Isono Y., Irie R., Kushida N., Yoneyama T., Otsuka R., Kanda K.,
RA   Yokoi T., Kondo H., Wagatsuma M., Murakawa K., Ishida S., Ishibashi T.,
RA   Takahashi-Fujii A., Tanase T., Nagai K., Kikuchi H., Nakai K., Isogai T.,
RA   Sugano S.;
RT   "Diversification of transcriptional modulation: large-scale identification
RT   and characterization of putative alternative promoters of human genes.";
RL   Genome Res. 16:55-65(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND IDENTIFICATION.
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; DB010820; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AC015908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471108; EAW89991.1; -; Genomic_DNA.
DR   EMBL; BC015790; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BC041634; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; A6NJY4; -.
DR   SMR; A6NJY4; -.
DR   BioMuta; -; -.
DR   BioMuta; TMEM238L; -.
DR   PaxDb; A6NJY4; -.
DR   PRIDE; A6NJY4; -.
DR   Ensembl; ENST00000581851.1; ENSP00000490566.1; ENSG00000263429.3.
DR   MANE-Select; ENST00000581851.2; ENSP00000490566.1; NM_001388428.1; NP_001375357.1.
DR   GeneCards; TMEM238L; -.
DR   HGNC; HGNC:44356; TMEM238L.
DR   neXtProt; NX_A6NJY4; -.
DR   OpenTargets; ENSG00000263429; -.
DR   VEuPathDB; HostDB:ENSG00000263429; -.
DR   GeneTree; ENSGT00940000164189; -.
DR   OMA; WDFLVYT; -.
DR   Pharos; A6NJY4; Tdark.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; A6NJY4; protein.
DR   Bgee; ENSG00000263429; Expressed in mucosa of transverse colon and 68 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029365; TMEM238.
DR   PANTHER; PTHR28613; PTHR28613; 1.
DR   Pfam; PF15125; TMEM238; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..79
FT                   /note="Transmembrane protein 238-like"
FT                   /id="PRO_0000345409"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        14
FT                   /note="R -> C (in Ref. 1; DB010820 and 4; BC015790/
FT                   BC041634)"
SQ   SEQUENCE   79 AA;  8766 MW;  47D1B3C0D9F8B638 CRC64;
     MLLGSLWGRC HPGRCALFLI LALLLDAVGL VLLLLGILAP LSSWDFFIYT GALILALSLL
     LWIIWYSLNI EVSPEKLDL