BPC2_ARATH
ID BPC2_ARATH Reviewed; 279 AA.
AC Q9LDE2; Q2PQS1;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Protein BASIC PENTACYSTEINE2 {ECO:0000303|PubMed:21435046};
DE Short=AtBPC2 {ECO:0000303|PubMed:21435046};
DE AltName: Full=GAGA-binding transcriptional activator BBR/BPC2 {ECO:0000303|Ref.6};
GN Name=BPC2 {ECO:0000303|PubMed:21435046};
GN Synonyms=BBR {ECO:0000303|PubMed:12795701};
GN OrderedLocusNames=At1g14685 {ECO:0000312|Araport:AT1G14685};
GN ORFNames=F10B6.5 {ECO:0000312|EMBL:AAF79219.1},
GN T5E21.17 {ECO:0000312|EMBL:AAF63172.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=cv. Shokei;
RX PubMed=12795701; DOI=10.1046/j.1365-313x.2003.01767.x;
RA Santi L., Wang Y., Stile M.R., Berendzen K.W., Wanke D., Roig C., Pozzi C.,
RA Mueller K., Mueller J., Rohde W., Salamini F.;
RT "The GA octodinucleotide repeat binding factor BBR participates in the
RT transcriptional regulation of the homeobox gene Bkn3.";
RL Plant J. 34:813-826(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DNA-BINDING, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14731261; DOI=10.1046/j.1365-313x.2003.01971.x;
RA Meister R.J., Williams L.A., Monfared M.M., Gallagher T.L., Kraft E.A.,
RA Nelson C.G., Gasser C.S.;
RT "Definition and interactions of a positive regulatory element of the
RT Arabidopsis INNER NO OUTER promoter.";
RL Plant J. 37:426-438(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP GENE FAMILY.
RA Bloss U., Hohenstatt M.L., Hummel S., Harter K., Wanke D.;
RT "The plant specific BPC/BBR family of GAGA-repeat binding proteins.";
RL (In) Proceedings of the 20th international conference on Arabidopsis
RL research, abstract#084, Edinburgh (2009).
RN [7]
RP DNA-BINDING.
RX PubMed=21108821; DOI=10.1186/1746-4811-6-25;
RA Brand L.H., Kirchler T., Hummel S., Chaban C., Wanke D.;
RT "DPI-ELISA: a fast and versatile method to specify the binding of plant
RT transcription factors to DNA in vitro.";
RL Plant Methods 6:25-25(2010).
RN [8]
RP TISSUE SPECIFICITY.
RX PubMed=21435046; DOI=10.1111/j.1365-313x.2011.04562.x;
RA Monfared M.M., Simon M.K., Meister R.J., Roig-Villanova I., Kooiker M.,
RA Colombo L., Fletcher J.C., Gasser C.S.;
RT "Overlapping and antagonistic activities of BASIC PENTACYSTEINE genes
RT affect a range of developmental processes in Arabidopsis.";
RL Plant J. 66:1020-1031(2011).
CC -!- FUNCTION: Transcriptional regulator that specifically binds to GA-rich
CC elements (GAGA-repeats) present in regulatory sequences of genes
CC involved in developmental processes. {ECO:0000269|PubMed:14731261}.
CC -!- INTERACTION:
CC Q9LDE2; Q17TI5: BRX; NbExp=3; IntAct=EBI-15215888, EBI-4426649;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, leaves and pistils.
CC Detected in the base of flowers and tips of carpels, in sepal and petal
CC vasculature, in pollen grains, in young rosette, in the lateral and tip
CC of primary roots, and in ovule at the exception of the outer
CC integument. {ECO:0000269|PubMed:14731261, ECO:0000269|PubMed:21435046}.
CC -!- SIMILARITY: Belongs to the BBR/BPC family. {ECO:0000305}.
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DR EMBL; DQ307036; ABC25617.1; -; Genomic_DNA.
DR EMBL; DQ307037; ABC25618.1; -; mRNA.
DR EMBL; AY380568; AAR25822.1; -; mRNA.
DR EMBL; AC006917; AAF79219.1; -; Genomic_DNA.
DR EMBL; AC010657; AAF63172.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29202.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29203.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29204.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58904.1; -; Genomic_DNA.
DR EMBL; AY058073; AAL24181.1; -; mRNA.
DR EMBL; AY090305; AAL90966.1; -; mRNA.
DR RefSeq; NP_001321304.1; NM_001332132.1.
DR RefSeq; NP_563955.1; NM_101336.4.
DR RefSeq; NP_849662.1; NM_179331.3.
DR RefSeq; NP_973828.1; NM_202099.1.
DR AlphaFoldDB; Q9LDE2; -.
DR BioGRID; 23271; 5.
DR IntAct; Q9LDE2; 5.
DR STRING; 3702.AT1G14685.3; -.
DR PaxDb; Q9LDE2; -.
DR PRIDE; Q9LDE2; -.
DR ProteomicsDB; 240476; -.
DR EnsemblPlants; AT1G14685.1; AT1G14685.1; AT1G14685.
DR EnsemblPlants; AT1G14685.2; AT1G14685.2; AT1G14685.
DR EnsemblPlants; AT1G14685.3; AT1G14685.3; AT1G14685.
DR EnsemblPlants; AT1G14685.4; AT1G14685.4; AT1G14685.
DR GeneID; 838031; -.
DR Gramene; AT1G14685.1; AT1G14685.1; AT1G14685.
DR Gramene; AT1G14685.2; AT1G14685.2; AT1G14685.
DR Gramene; AT1G14685.3; AT1G14685.3; AT1G14685.
DR Gramene; AT1G14685.4; AT1G14685.4; AT1G14685.
DR KEGG; ath:AT1G14685; -.
DR Araport; AT1G14685; -.
DR TAIR; locus:2823945; AT1G14685.
DR eggNOG; ENOG502QRPH; Eukaryota.
DR HOGENOM; CLU_039119_2_0_1; -.
DR InParanoid; Q9LDE2; -.
DR OMA; HHAEPPI; -.
DR OrthoDB; 1257222at2759; -.
DR PhylomeDB; Q9LDE2; -.
DR PRO; PR:Q9LDE2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LDE2; baseline and differential.
DR Genevisible; Q9LDE2; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IDA:TAIR.
DR GO; GO:1901002; P:positive regulation of response to salt stress; IGI:TAIR.
DR GO; GO:0050793; P:regulation of developmental process; IGI:TAIR.
DR GO; GO:0080157; P:regulation of plant-type cell wall organization or biogenesis; IGI:TAIR.
DR GO; GO:0009723; P:response to ethylene; IGI:TAIR.
DR InterPro; IPR010409; GAGA-bd_tscrpt_act.
DR PANTHER; PTHR31421; PTHR31421; 1.
DR Pfam; PF06217; GAGA_bind; 1.
DR SMART; SM01226; GAGA_bind; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..279
FT /note="Protein BASIC PENTACYSTEINE2"
FT /id="PRO_0000413436"
FT REGION 126..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 151
FT /note="N -> S (in strain: cv. Shokei)"
FT VARIANT 161
FT /note="N -> D (in strain: cv. Shokei)"
SQ SEQUENCE 279 AA; 31169 MW; BAB996037E04D372 CRC64;
MDDDGFRNWG YYEPAAATFK GNLGLQLMST IDRNTKPFLP GRDPNLMMGP NGSYHHQEPP
IHMSYNWINQ QKDKFFNMLP VTTATPNYGN VLPETSSAPS MQMNLHHHLQ TEENPVKLEE
EIVVQTKKRK TNAKAGSTPK AKKPRKPKDE NSNNNNNNNT NVTRVKPAKK SVDLVINGVS
MDISGLPVPI CTCTGAPQQC YRWGCGGWQS ACCTTNISMH PLPMSTKRRG ARISGRKMSQ
GAFKKVLEKL ASDGFNFGNP IDLKSHWARH GTNKFVTIR
