ID   T251A_XENLA             Reviewed;         131 AA.
AC   Q66J17;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Transmembrane protein 251-A;
GN   Name=tmem251-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Golgi apparatus {ECO:0000250|UniProtKB:Q8N6I4}.
CC   -!- SIMILARITY: Belongs to the TMEM251 family. {ECO:0000305}.
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DR   EMBL; BC081102; AAH81102.1; -; mRNA.
DR   RefSeq; NP_001087696.1; NM_001094227.1.
DR   AlphaFoldDB; Q66J17; -.
DR   DNASU; 447520; -.
DR   GeneID; 447520; -.
DR   KEGG; xla:447520; -.
DR   CTD; 447520; -.
DR   Xenbase; XB-GENE-6078298; tmem251.L.
DR   OrthoDB; 1528152at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 447520; Expressed in blastula and 19 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028024; TMEM251.
DR   PANTHER; PTHR31925; PTHR31925; 1.
DR   Pfam; PF15190; TMEM251; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..131
FT                   /note="Transmembrane protein 251-A"
FT                   /id="PRO_0000359886"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   131 AA;  15399 MW;  3680131F4C4D13FE CRC64;
     MMNFRQRMGW IGVSLYLFVS AAAFYYVFEI NDTYNKLALE HVQLKPQEPH RGTTWTHSLK
     ARLLSLPFWL WATLFLIPYF QVFLFLYSCT RADPKTVGYC IIPICLAIIC NRHQSFVRAS
     NQISRLQLID T