BPC4_ARATH
ID BPC4_ARATH Reviewed; 296 AA.
AC Q8S8C6; Q6U1M9;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Protein BASIC PENTACYSTEINE4;
DE Short=AtBPC4;
GN Name=BPC4; OrderedLocusNames=At2g21240; ORFNames=F7O24.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DNA-BINDING, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14731261; DOI=10.1046/j.1365-313x.2003.01971.x;
RA Meister R.J., Williams L.A., Monfared M.M., Gallagher T.L., Kraft E.A.,
RA Nelson C.G., Gasser C.S.;
RT "Definition and interactions of a positive regulatory element of the
RT Arabidopsis INNER NO OUTER promoter.";
RL Plant J. 37:426-438(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia; TISSUE=Rosette leaf;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP GENE FAMILY.
RA Bloss U., Hohenstatt M.L., Hummel S., Harter K., Wanke D.;
RT "The plant specific BPC/BBR family of GAGA-repeat binding proteins.";
RL (In) Proceedings of the 20th international conference on Arabidopsis
RL research, abstract#084, Edinburgh (2009).
RN [9]
RP TISSUE SPECIFICITY.
RX PubMed=21435046; DOI=10.1111/j.1365-313x.2011.04562.x;
RA Monfared M.M., Simon M.K., Meister R.J., Roig-Villanova I., Kooiker M.,
RA Colombo L., Fletcher J.C., Gasser C.S.;
RT "Overlapping and antagonistic activities of BASIC PENTACYSTEINE genes
RT affect a range of developmental processes in Arabidopsis.";
RL Plant J. 66:1020-1031(2011).
RN [10]
RP DOMAIN DIMERIZATION, AND SUBUNIT.
RX PubMed=21347358; DOI=10.1371/journal.pone.0016070;
RA Wanke D., Hohenstatt M.L., Dynowski M., Bloss U., Hecker A., Elgass K.,
RA Hummel S., Hahn A., Caesar K., Schleifenbaum F., Harter K., Berendzen K.W.;
RT "Alanine zipper-like coiled-coil domains are necessary for homotypic
RT dimerization of plant GAGA-factors in the nucleus and nucleolus.";
RL PLoS ONE 6:E16070-E16070(2011).
CC -!- FUNCTION: Transcriptional regulator that specifically binds to GA-rich
CC elements (GAGA-repeats) present in regulatory sequences of genes
CC involved in developmental processes. {ECO:0000269|PubMed:14731261}.
CC -!- SUBUNIT: Homodimer. Heterodimer with BPC4.
CC {ECO:0000269|PubMed:21347358}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in seedlings, leaves and pistils.
CC Detected in the base of flowers and tips of carpels, in sepal and petal
CC vasculature, in anthers, in young rosette, in the lateral and primary
CC roots, and in the whole ovule. {ECO:0000269|PubMed:14731261,
CC ECO:0000269|PubMed:21435046}.
CC -!- DOMAIN: Alanine-zipper domain is involved in homo- or hetero-
CC dimerization via electrostatic interaction.
CC {ECO:0000269|PubMed:21347358}.
CC -!- SIMILARITY: Belongs to the BBR/BPC family. {ECO:0000305}.
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DR EMBL; AY380570; AAR25824.1; -; mRNA.
DR EMBL; AC007142; AAM15408.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07147.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07148.1; -; Genomic_DNA.
DR EMBL; BT026109; ABG48465.1; -; mRNA.
DR EMBL; AK229090; BAF00970.1; -; mRNA.
DR EMBL; AK317165; BAH19851.1; -; mRNA.
DR EMBL; AY084554; AAM61121.1; -; mRNA.
DR PIR; H84598; H84598.
DR RefSeq; NP_565503.1; NM_127696.4.
DR RefSeq; NP_850012.1; NM_179681.2.
DR AlphaFoldDB; Q8S8C6; -.
DR SMR; Q8S8C6; -.
DR BioGRID; 2016; 4.
DR STRING; 3702.AT2G21240.1; -.
DR PaxDb; Q8S8C6; -.
DR PRIDE; Q8S8C6; -.
DR ProteomicsDB; 240701; -.
DR EnsemblPlants; AT2G21240.1; AT2G21240.1; AT2G21240.
DR EnsemblPlants; AT2G21240.2; AT2G21240.2; AT2G21240.
DR GeneID; 816663; -.
DR Gramene; AT2G21240.1; AT2G21240.1; AT2G21240.
DR Gramene; AT2G21240.2; AT2G21240.2; AT2G21240.
DR KEGG; ath:AT2G21240; -.
DR Araport; AT2G21240; -.
DR TAIR; locus:2053086; AT2G21240.
DR eggNOG; ENOG502R48X; Eukaryota.
DR HOGENOM; CLU_039119_0_0_1; -.
DR InParanoid; Q8S8C6; -.
DR OMA; RHKMEYY; -.
DR OrthoDB; 1076395at2759; -.
DR PhylomeDB; Q8S8C6; -.
DR PRO; PR:Q8S8C6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8S8C6; baseline and differential.
DR Genevisible; Q8S8C6; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0050793; P:regulation of developmental process; IGI:TAIR.
DR GO; GO:0009723; P:response to ethylene; IGI:TAIR.
DR InterPro; IPR010409; GAGA-bd_tscrpt_act.
DR PANTHER; PTHR31421; PTHR31421; 1.
DR Pfam; PF06217; GAGA_bind; 1.
DR SMART; SM01226; GAGA_bind; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..296
FT /note="Protein BASIC PENTACYSTEINE4"
FT /id="PRO_0000413438"
FT REGION 55..90
FT /note="Alanine-zipper"
FT COILED 66..97
FT /evidence="ECO:0000255"
FT VARIANT 19
FT /note="G -> V (in strain: cv. Landsberg erecta)"
SQ SEQUENCE 296 AA; 33307 MW; 90D5C72A6CA48757 CRC64;
MENGGQYDNA RFKPDYFKGA QSMWNMIPQH QIKEQHNALV MNKKIMSILA ERDAAVHERN
QAVSAKKEAV AARDEALQQR DKALSERDKA LIERDNAYAA LQHHENSLNF ALSGGKCVDG
DDCFGIGEPH KLEVFPLSTI PPEVTNTKVV NKRKKENKQG LSKVKKVGED LNRRVPAPGK
KSRTDWDSQD VGLNLVTFDE TTMPVPMCSC TGSTRQCYKW GNGGWQSSCC TTTLSQYPLP
QMPNKRHSRM GGRKMSGNVF SRLLSRLSAE GYDLSCPVDL KDYWARHGTN RYITIK
