T2AG_MAGO7
ID T2AG_MAGO7 Reviewed; 116 AA.
AC A4QW40; G4N5H3;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Transcription initiation factor IIA subunit 2;
DE AltName: Full=General transcription factor IIA subunit 2;
DE AltName: Full=Transcription initiation factor IIA small chain;
GN Name=TOA2; ORFNames=MGG_06107;
OS Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS fungus) (Pyricularia oryzae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX NCBI_TaxID=242507;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX PubMed=15846337; DOI=10.1038/nature03449;
RA Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL Nature 434:980-986(2005).
CC -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC polymerase II and plays an important role in transcriptional
CC activation. TFIIA in a complex with tbp mediates transcriptional
CC activity (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: TFIIA is a heterodimer composed of the large TOA1 and the
CC small TOA2 subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 2 family. {ECO:0000305}.
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DR EMBL; CM001233; EHA52166.1; -; Genomic_DNA.
DR RefSeq; XP_003711973.1; XM_003711925.1.
DR AlphaFoldDB; A4QW40; -.
DR SMR; A4QW40; -.
DR STRING; 318829.MGG_06107T0; -.
DR EnsemblFungi; MGG_06107T0; MGG_06107T0; MGG_06107.
DR GeneID; 2684291; -.
DR KEGG; mgr:MGG_06107; -.
DR VEuPathDB; FungiDB:MGG_06107; -.
DR eggNOG; KOG3463; Eukaryota.
DR HOGENOM; CLU_112964_3_1_1; -.
DR InParanoid; A4QW40; -.
DR OMA; QYYELYR; -.
DR OrthoDB; 1589933at2759; -.
DR Proteomes; UP000009058; Chromosome 3.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:EnsemblFungi.
DR GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:EnsemblFungi.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:EnsemblFungi.
DR GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IEA:EnsemblFungi.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:EnsemblFungi.
DR CDD; cd10014; TFIIA_gamma_C; 1.
DR CDD; cd10145; TFIIA_gamma_N; 1.
DR Gene3D; 1.10.287.190; -; 1.
DR Gene3D; 2.30.18.10; -; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR009088; TFIIA_b-brl.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015871; TFIIA_gsu_C.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; PTHR10966; 1.
DR Pfam; PF02751; TFIIA_gamma_C; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF50784; SSF50784; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..116
FT /note="Transcription initiation factor IIA subunit 2"
FT /id="PRO_0000406208"
SQ SEQUENCE 116 AA; 13235 MW; 8718005B542DA7B2 CRC64;
MATKKEETFY ELYRRTSLGI CLTDALDDLI TNDRINPQLA MKILANFDRV VAETLQEKVK
ARLQFKGALD NYRFCDDVWT FVIKNINFKL DGGNQTIQAD KVKIVSCNAK RPGTDA