ID   T2AG_ONCMY              Reviewed;         108 AA.
AC   Q90YG6;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Transcription initiation factor IIA subunit 2;
DE   AltName: Full=General transcription factor IIA subunit 2;
DE   AltName: Full=Transcription initiation factor IIA gamma chain;
DE            Short=TFIIA-gamma;
GN   Name=gtf2a2;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Pleguezuelos O., Secombes C.J.;
RT   "Screening a rainbow trout (Oncorhynchus mykiss) cDNA library.";
RL   Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC       polymerase II and plays an important role in transcriptional
CC       activation. TFIIA in a complex with TBP mediates transcriptional
CC       activity (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: TFIIA is a heterodimer of the large unprocessed subunit 1 and
CC       a small subunit gamma. It was originally believed to be a heterotrimer
CC       of an alpha, a beta and a gamma subunit. Interacts with NCOA6 general
CC       coactivator. TFIIA forms a complex with TBP (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- SIMILARITY: Belongs to the TFIIA subunit 2 family. {ECO:0000305}.
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DR   EMBL; AJ312341; CAC44187.1; -; mRNA.
DR   RefSeq; NP_001117838.1; NM_001124366.1.
DR   AlphaFoldDB; Q90YG6; -.
DR   SMR; Q90YG6; -.
DR   Ensembl; ENSOMYT00000072293; ENSOMYP00000066370; ENSOMYG00000030677.
DR   Ensembl; ENSOMYT00000123691; ENSOMYP00000134705; ENSOMYG00000065240.
DR   GeneID; 100136048; -.
DR   KEGG; omy:100136048; -.
DR   CTD; 2958; -.
DR   GeneTree; ENSGT00390000014572; -.
DR   OrthoDB; 1589933at2759; -.
DR   GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro.
DR   CDD; cd10014; TFIIA_gamma_C; 1.
DR   CDD; cd10145; TFIIA_gamma_N; 1.
DR   Gene3D; 1.10.287.190; -; 1.
DR   Gene3D; 2.30.18.10; -; 1.
DR   InterPro; IPR009083; TFIIA_a-hlx.
DR   InterPro; IPR009088; TFIIA_b-brl.
DR   InterPro; IPR003194; TFIIA_gsu.
DR   InterPro; IPR015871; TFIIA_gsu_C.
DR   InterPro; IPR015872; TFIIA_gsu_N.
DR   PANTHER; PTHR10966; PTHR10966; 1.
DR   Pfam; PF02751; TFIIA_gamma_C; 1.
DR   Pfam; PF02268; TFIIA_gamma_N; 1.
DR   PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR   SUPFAM; SSF50784; SSF50784; 1.
PE   3: Inferred from homology;
KW   Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..108
FT                   /note="Transcription initiation factor IIA subunit 2"
FT                   /id="PRO_0000194045"
SQ   SEQUENCE   108 AA;  12284 MW;  52A95FE4B3F96673 CRC64;
     MAYQLYRNTT LGNSLQESLD ELIQTQQITP QLALQVLLQF DKAINTALAN RVRNRVNFKG
     SLNTYRFCDN VWTFVLNDVE FREVTDLVKV DKVKIVACDG KNTGNAAE