T2AG_ORYSI
ID T2AG_ORYSI Reviewed; 106 AA.
AC A2XZI2; Q5SDB6; Q65X27; Q7FPX2; Q94HL5;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 2.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Transcription initiation factor IIA subunit 2;
DE AltName: Full=General transcription factor IIA subunit 2;
DE AltName: Full=Transcription initiation factor IIA gamma chain;
DE Short=TFIIA-gamma;
GN Name=TFIIAy; Synonyms=XA5; ORFNames=OsI_017475;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. IR24;
RX PubMed=12677405; DOI=10.1007/s00122-003-1231-2;
RA Blair M.W., Garris A.J., Iyer A.S., Chapman B., Kresovich S., McCouch S.R.;
RT "High resolution genetic mapping and candidate gene identification at the
RT xa5 locus for bacterial blight resistance in rice (Oryza sativa L.).";
RL Theor. Appl. Genet. 107:62-73(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND VARIANT GLU-39.
RC STRAIN=cv. Aus-Boro, and cv. IRBB5;
RX PubMed=15597740; DOI=10.1094/mpmi.2004.17.12.1348;
RA Iyer A.S., McCouch S.R.;
RT "The rice bacterial blight resistance gene xa5 encodes a novel form of
RT disease resistance.";
RL Mol. Plant Microbe Interact. 17:1348-1354(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: TFIIA is a component of the transcription machinery of RNA
CC polymerase II and plays an important role in transcriptional
CC activation. TFIIA in a complex with TBP mediates transcriptional
CC activity (By similarity). Protein involved in the resistance to
CC X.oryzae. {ECO:0000250, ECO:0000269|PubMed:15597740}.
CC -!- SUBUNIT: TFIIA is a heterodimer of the large unprocessed subunit 1 and
CC a small subunit gamma. It was originally believed to be a heterotrimer
CC of an alpha, a beta and a gamma subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- MISCELLANEOUS: The displayed sequence corresponds to the form of the
CC protein present in strains susceptible to X.oryzae. Substitution of
CC Val-39 to Glu-39 in cultivar indica IRBB5 confers resistance to
CC X.oryzae.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 2 family. {ECO:0000305}.
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DR EMBL; AF532975; AAO33769.1; -; Genomic_DNA.
DR EMBL; AY643716; AAV53715.1; -; mRNA.
DR EMBL; AY643717; AAV53716.1; -; mRNA.
DR EMBL; CM000130; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A2XZI2; -.
DR SMR; A2XZI2; -.
DR STRING; 39946.A2XZI2; -.
DR EnsemblPlants; BGIOSGA019022-TA; BGIOSGA019022-PA; BGIOSGA019022.
DR Gramene; BGIOSGA019022-TA; BGIOSGA019022-PA; BGIOSGA019022.
DR HOGENOM; CLU_112964_3_1_1; -.
DR OMA; QYYELYR; -.
DR Proteomes; UP000007015; Chromosome 5.
DR ExpressionAtlas; A2XZI2; differential.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd10014; TFIIA_gamma_C; 1.
DR CDD; cd10145; TFIIA_gamma_N; 1.
DR Gene3D; 1.10.287.190; -; 1.
DR Gene3D; 2.30.18.10; -; 1.
DR InterPro; IPR009083; TFIIA_a-hlx.
DR InterPro; IPR009088; TFIIA_b-brl.
DR InterPro; IPR003194; TFIIA_gsu.
DR InterPro; IPR015871; TFIIA_gsu_C.
DR InterPro; IPR015872; TFIIA_gsu_N.
DR PANTHER; PTHR10966; PTHR10966; 1.
DR Pfam; PF02751; TFIIA_gamma_C; 1.
DR Pfam; PF02268; TFIIA_gamma_N; 1.
DR PIRSF; PIRSF009415; Hum_TFIIA_gamma; 1.
DR SUPFAM; SSF50784; SSF50784; 1.
PE 3: Inferred from homology;
KW Initiation factor; Nucleus; Plant defense; Protein biosynthesis;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..106
FT /note="Transcription initiation factor IIA subunit 2"
FT /id="PRO_0000303665"
FT VARIANT 39
FT /note="V -> E (in strain: cv. IRBB5; confers resistance to
FT X.oryzae)"
FT /evidence="ECO:0000269|PubMed:15597740"
SQ SEQUENCE 106 AA; 11970 MW; 1D32E02DD2D7117E CRC64;
MATFELYRRS TIGMCLTETL DEMVSSGTLS PELAIQVLVQ FDKSMTEALE NQVKSKVSIK
GHLHTYRFCD NVWTFILTEA SFKNEETTEQ VGKVKIVACD SKLLSQ
