ID   T2R36_HUMAN             Reviewed;         309 AA.
AC   P0DTE0;
DT   12-AUG-2020, integrated into UniProtKB/Swiss-Prot.
DT   12-AUG-2020, sequence version 1.
DT   03-AUG-2022, entry version 8.
DE   RecName: Full=Putative taste receptor type 2 member 36 {ECO:0000305};
DE            Short=T2R36 {ECO:0000303|Ref.1};
DE            Short=hGR36 {ECO:0000303|Ref.1};
GN   Name=TAS2R36 {ECO:0000312|HGNC:HGNC:19115};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Zuker C.S., Adler J.E., Ryba N., Mueller K., Hoon M.;
RT   "T2r taste receptor family.";
RL   Patent number WO0118050, 15-MAR-2001.
CC   -!- FUNCTION: Putative taste receptor which may play a role in the
CC       perception of bitterness. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor T2R family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Product of a dubious gene prediction. Zuker et al. identified
CC       this gene on chromosome 12. However, it is not currently present on the
CC       reference genome assembly (GRCh38/hg38). {ECO:0000305}.
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DR   EMBL; AX097755; -; NOT_ANNOTATED_CDS; Unassigned_DNA.
DR   AlphaFoldDB; P0DTE0; -.
DR   SMR; P0DTE0; -.
DR   GlyGen; P0DTE0; 2 sites.
DR   GeneCards; TAS2R36; -.
DR   HGNC; HGNC:19115; TAS2R36.
DR   neXtProt; NX_P0DTE0; -.
DR   Proteomes; UP000005640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   InterPro; IPR007960; TAS2R.
DR   Pfam; PF05296; TAS2R; 1.
PE   5: Uncertain;
KW   G-protein coupled receptor; Glycoprotein; Membrane; Receptor;
KW   Reference proteome; Sensory transduction; Taste; Transducer; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Putative taste receptor type 2 member 36"
FT                   /id="PRO_0000450482"
FT   TOPO_DOM        1
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        23..46
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..79
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        101..126
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        148..181
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        203..229
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        251..259
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        281..309
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   CARBOHYD        161
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        176
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   309 AA;  35420 MW;  894931EA28A75A58 CRC64;
     MICFLLIILS ILVVFAFVLG NFSNGFIALV NVIDWVKRQK ISSADQILTA LVVSRVGLLW
     VILLHWYSNV LNSALYSSEV IIFISNAWAI INHFSIWLAT SLSIFYLLKI VNFSRLIFHH
     LKRKAKSVVL VIVLGPLVFL VCHLVMKHTY INVWTKEYEG NVTWKIKLRN AIHLSNLTVS
     TLANLIPFTL TLISFLLLIY SLCKHLKKMQ LHGKGSQDPS TKVHIKALQT VTSFLLLCAI
     YFLSMIISVC NFGRLEKQPV FMFCQAIIFS YPSTHPFILI LGNKKLKQIF LSVFWQMRYW
     VKGEKPSSP