ID   T2RMN_MYCPN             Reviewed;         165 AA.
AC   P75453;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative type II restriction enzyme and methyltransferase RM.MpnORF109P N-terminus {ECO:0000303|PubMed:12654995};
GN   OrderedLocusNames=MPN_109; ORFNames=C09_orf165, MP045;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=11271496;
RX   DOI=10.1002/1522-2683(200011)21:17<3765::aid-elps3765>3.0.co;2-6;
RA   Regula J.T., Ueberle B., Boguth G., Goerg A., Schnoelzer M., Herrmann R.,
RA   Frank R.;
RT   "Towards a two-dimensional proteome map of Mycoplasma pneumoniae.";
RL   Electrophoresis 21:3765-3780(2000).
RN   [3]
RP   NOMENCLATURE.
RX   PubMed=12654995; DOI=10.1093/nar/gkg274;
RA   Roberts R.J., Belfort M., Bestor T., Bhagwat A.S., Bickle T.A.,
RA   Bitinaite J., Blumenthal R.M., Degtyarev S.K., Dryden D.T., Dybvig K.,
RA   Firman K., Gromova E.S., Gumport R.I., Halford S.E., Hattman S.,
RA   Heitman J., Hornby D.P., Janulaitis A., Jeltsch A., Josephsen J., Kiss A.,
RA   Klaenhammer T.R., Kobayashi I., Kong H., Krueger D.H., Lacks S.,
RA   Marinus M.G., Miyahara M., Morgan R.D., Murray N.E., Nagaraja V.,
RA   Piekarowicz A., Pingoud A., Raleigh E., Rao D.N., Reich N., Repin V.E.,
RA   Selker E.U., Shaw P.C., Stein D.C., Stoddard B.L., Szybalski W.,
RA   Trautner T.A., Van Etten J.L., Vitor J.M., Wilson G.G., Xu S.Y.;
RT   "A nomenclature for restriction enzymes, DNA methyltransferases, homing
RT   endonucleases and their genes.";
RL   Nucleic Acids Res. 31:1805-1812(2003).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY, INDUCTION, AND DISCUSSION OF SEQUENCE.
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=23300489; DOI=10.1371/journal.pgen.1003191;
RA   Lluch-Senar M., Luong K., Llorens-Rico V., Delgado J., Fang G., Spittle K.,
RA   Clark T.A., Schadt E., Turner S.W., Korlach J., Serrano L.;
RT   "Comprehensive methylome characterization of Mycoplasma genitalium and
RT   Mycoplasma pneumoniae at single-base resolution.";
RL   PLoS Genet. 9:e1003191-e1003191(2013).
CC   -!- FUNCTION: Corresponds to the N-terminus of a putative G subtype type II
CC       restriction/methylase subunit. {ECO:0000303|PubMed:12654995}.
CC   -!- INDUCTION: Detected after 6 and 96 hours growth, there is no change in
CC       protein levels (at protein level). {ECO:0000269|PubMed:23300489}.
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DR   EMBL; U00089; AAB95693.1; -; Genomic_DNA.
DR   PIR; S73371; S73371.
DR   RefSeq; NP_109797.1; NC_000912.1.
DR   RefSeq; WP_010874466.1; NC_000912.1.
DR   AlphaFoldDB; P75453; -.
DR   SMR; P75453; -.
DR   EnsemblBacteria; AAB95693; AAB95693; MPN_109.
DR   KEGG; mpn:MPN_109; -.
DR   PATRIC; fig|272634.6.peg.115; -.
DR   HOGENOM; CLU_1609014_0_0_14; -.
DR   BioCyc; MPNE272634:G1GJ3-186-MON; -.
DR   Proteomes; UP000000808; Chromosome.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..165
FT                   /note="Putative type II restriction enzyme and
FT                   methyltransferase RM.MpnORF109P N-terminus"
FT                   /id="PRO_0000210647"
SQ   SEQUENCE   165 AA;  19820 MW;  4B8DB2142A13C1A9 CRC64;
     MKFKLNFHEK INQKDCWQSL IDHKERSYSL DFVNNTEKEL PLIYGYEVKD FENHGVKIGY
     TTCKPSDKIQ SAIEERILSQ EKEFRFLDEN IEKIEEVKVI FWAIAINEKD ESFKDYSLHS
     FIKEKNLLKE SQAGGEWFIV DENKDKFEYL SQIFRQFRAP SLFKK