ID   ABT1_PONAB              Reviewed;         272 AA.
AC   Q5R9Y3;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Activator of basal transcription 1;
GN   Name=ABT1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Coud be a novel TATA-binding protein (TBP) which can function
CC       as a basal transcription activator. Can act as a regulator of basal
CC       transcription for class II genes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ESF1/ABTAP. Interacts with IGHMBP2.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Nucleus, nucleolus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ESF2/ABP1 family. {ECO:0000305}.
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DR   EMBL; CR859247; CAH91427.1; -; mRNA.
DR   RefSeq; NP_001125836.1; NM_001132364.1.
DR   AlphaFoldDB; Q5R9Y3; -.
DR   STRING; 9601.ENSPPYP00000018265; -.
DR   GeneID; 100172765; -.
DR   KEGG; pon:100172765; -.
DR   CTD; 29777; -.
DR   eggNOG; KOG3152; Eukaryota.
DR   InParanoid; Q5R9Y3; -.
DR   OrthoDB; 1377351at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   CDD; cd12263; RRM_ABT1_like; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR039119; ABT1/Esf2.
DR   InterPro; IPR034353; ABT1/ESF2_RRM.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   PANTHER; PTHR12311; PTHR12311; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Coiled coil; DNA-binding; Nucleus; Reference proteome;
KW   RNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..272
FT                   /note="Activator of basal transcription 1"
FT                   /id="PRO_0000233170"
FT   DOMAIN          46..142
FT                   /note="RRM"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          197..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          161..191
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..240
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9ULW3"
SQ   SEQUENCE   272 AA;  31050 MW;  E218CB570E06FDDF CRC64;
     MEAEESEKAA TEQEPLKGTE QTLDAEEEQE ESEDAACGSK KRVVPGIVYL GHIPPRFRPL
     HVRNLLSAYG EVGRVFFQAE DRFVRRKKKA AAAAGGKKRS YSKDYTEGWV EFRDKRIAKR
     VAASLHNTPM GARRRSPFRY DLWNLKYLHR FTWSHLSEHL AFERQVRRQR LRAEVAQAKR
     ETDFYLQSVE RGQRFLAADG DPARPDGSWT FAQRPTEQEL RAQKAARPGG RERARLVTAQ
     DKARSNKGLL ARIFGAPPPS ESMEGPSLVR DS