T408_BURM1
ID T408_BURM1 Reviewed; 518 AA.
AC Q51649; A9AMU0;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Putative transposase for insertion sequence IS408;
GN OrderedLocusNames=Bmul_4730, BMULJ_03785;
GN and
GN OrderedLocusNames=Bmul_5628, BMULJ_05881;
GN and
GN OrderedLocusNames=Bmul_6206, BMULJ_06213;
OS Burkholderia multivorans (strain ATCC 17616 / 249).
OG Plasmid pBMUL01, and Plasmid pTGL1.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=395019;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7518087; DOI=10.1006/plas.1994.1015;
RA Byrne A.M., Lessie T.G.;
RT "Characteristics of IS401, a new member of the IS3 family implicated in
RT plasmid rearrangements in Pseudomonas cepacia.";
RL Plasmid 31:138-147(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17616 / 249;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J.,
RA Richardson P.;
RT "Complete sequence of chromosome 2 of Burkholderia multivorans ATCC
RT 17616.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17616 / 249;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J.,
RA Richardson P.;
RT "Complete sequence of chromosome 3 of Burkholderia multivorans ATCC
RT 17616.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17616 / 249; PLASMID=pBMUL01;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Tiedje J.,
RA Richardson P.;
RT "Complete sequence of plasmid 1 of Burkholderia multivorans ATCC 17616.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17616 / 249; PLASMID=pTGL1;
RA Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E.,
RA Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N.,
RA Hattori M., Tsuda M.;
RT "Complete genome sequence of Burkholderia multivorans ATCC 17616.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the transposition of the insertion element.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the transposase IS21/IS408/IS1162 family.
CC {ECO:0000305}.
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DR EMBL; L09108; AAA25863.1; -; Genomic_DNA.
DR EMBL; CP000869; ABX18406.1; -; Genomic_DNA.
DR EMBL; CP000870; ABX19298.1; -; Genomic_DNA.
DR EMBL; CP000871; ABX19859.1; -; Genomic_DNA.
DR EMBL; AP009386; BAG45646.1; -; Genomic_DNA.
DR EMBL; AP009387; BAG47689.1; -; Genomic_DNA.
DR EMBL; AP009388; BAG48003.1; -; Genomic_DNA.
DR RefSeq; WP_011875599.1; NC_010805.1.
DR AlphaFoldDB; Q51649; -.
DR STRING; 395019.Bmul_4730; -.
DR PRIDE; Q51649; -.
DR EnsemblBacteria; BAG45646; BAG45646; BMULJ_03785.
DR EnsemblBacteria; BAG47689; BAG47689; BMULJ_05881.
DR EnsemblBacteria; BAG48003; BAG48003; BMULJ_06213.
DR GeneID; 61089187; -.
DR KEGG; bmj:BMULJ_03785; -.
DR KEGG; bmj:BMULJ_05881; -.
DR KEGG; bmj:BMULJ_06213; -.
DR KEGG; bmu:Bmul_4730; -.
DR KEGG; bmu:Bmul_5628; -.
DR KEGG; bmu:Bmul_6206; -.
DR eggNOG; COG4584; Bacteria.
DR HOGENOM; CLU_020626_11_0_4; -.
DR OMA; MRQTHIA; -.
DR Proteomes; UP000008815; Chromosome 2.
DR Proteomes; UP000008815; Chromosome 3.
DR Proteomes; UP000008815; Plasmid pTGL1.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.10; -; 1.
DR InterPro; IPR017895; HTH_IS408/IS1162_type.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR PROSITE; PS50532; HTH_IS408; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Plasmid; Reference proteome;
KW Transposable element; Transposition.
FT CHAIN 1..518
FT /note="Putative transposase for insertion sequence IS408"
FT /id="PRO_0000075466"
FT DOMAIN 11..94
FT /note="HTH IS408-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00616"
FT DOMAIN 140..335
FT /note="Integrase catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
FT DNA_BIND 23..44
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00616"
FT REGION 496..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 58424 MW; 6C87292C2630C8E6 CRC64;
MPTPRMSMRK LKEVLRLKWA CGLTHRQISR AIGISVGAVS KFAAQASQAG LDWAAAEAMS
DDELDARLRP AATNAAATTT RRIEPDYTAL HRELRRKGVT LQLLWEEYAE ANPGQRTYRY
TQFCQKYKDW AKSIKRSMRQ QHRAGEKLFA DFAGPTVPVL ASDGGVEFEA HVFVAVLGAS
NYTFACATRT ETMADWIGSL CDALEFIGGV PELLVPDNPK ALIARPDRYE PGLGTTTQDF
VNHYGTAMLP ARPRKPQDKA KVEVGVQIVE RWVLARLRHY RFYSLAELNK AIAELIADLN
QRPFKRLEGN RREWFERLDQ PVLRPLPVRR YEIATFQKCR VNIDYHVDVG GHYYSVPHSL
ARQEVWARIT RHGVEILHGG KRVAAHARSR LKGKHTTIAE HMPAAHRAHM EWTPGRLLNW
GASVGPGAEA VVRHLLTNKP HPEMGYRACL GLLSLARKYG KHRLEAACQR ALKIGSPTRR
SVLSILEAGL DLQPSLPTTP AEWRSPEHEN VRGPDYYH
