T421_ECOLX
ID T421_ECOLX Reviewed; 371 AA.
AC P11901;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Transposase for insertion sequence element IS421;
OS Escherichia coli.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=B, and C;
RX PubMed=2542093; DOI=10.1016/0014-5793(89)80007-9;
RA Sato S., Nakada Y., Shiratsuchi A.;
RT "IS421, a new insertion sequence in Escherichia coli.";
RL FEBS Lett. 249:21-26(1989).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence
CC IS421.
CC -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
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DR EMBL; Y07501; CAA68802.1; -; Genomic_DNA.
DR PIR; S04880; S04880.
DR AlphaFoldDB; P11901; -.
DR STRING; 481805.EcolC_0936; -.
DR eggNOG; COG3385; Bacteria.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002559; Transposase_11.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Transposable element; Transposition.
FT CHAIN 1..371
FT /note="Transposase for insertion sequence element IS421"
FT /id="PRO_0000173295"
SQ SEQUENCE 371 AA; 40996 MW; 2BD731641192DF38 CRC64;
MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY GPGGMSSLRE
VTAWAQLHDV ATLSDVALLK RLRNAADWFG ILAAQTLAVR AAVTGCTSGK RLRLVDGTAI
SAPGGGSAEW RLHMGYDPHT CQFTDFELTD SRDAERLDRF AQTADEIRIA DRGFGSRPEC
IRSLAFGEAD YIVRVHWRGL RWLTAEGMRF DMMGFLRGLD CGKNGETTVM IGNSGNKKAG
APFPARLIAV SLPPEKALIS KTRLLSENRR KGRVVQAETL EAAGHVLLLT SLPEDEYSAE
QVADCYRLRW QIELAFKRLK SLLHLDALRA KEPELAKAWI FANLLAAFLI DDIIQPSLDF
PPRSAGSEKK N