ID   T4S18_BOVIN             Reviewed;         201 AA.
AC   Q3T110;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Transmembrane 4 L6 family member 18;
GN   Name=TM4SF18;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Mammary gland;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the L6 tetraspanin family. {ECO:0000305}.
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DR   EMBL; BC102174; AAI02175.1; -; mRNA.
DR   RefSeq; NP_001029459.1; NM_001034287.2.
DR   RefSeq; NP_001171653.1; NM_001184724.1.
DR   AlphaFoldDB; Q3T110; -.
DR   STRING; 9913.ENSBTAP00000026585; -.
DR   PaxDb; Q3T110; -.
DR   GeneID; 507280; -.
DR   KEGG; bta:507280; -.
DR   CTD; 116441; -.
DR   eggNOG; ENOG502QS18; Eukaryota.
DR   HOGENOM; CLU_087168_2_0_1; -.
DR   InParanoid; Q3T110; -.
DR   OrthoDB; 1169493at2759; -.
DR   TreeFam; TF331371; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   InterPro; IPR008661; L6_membrane.
DR   PANTHER; PTHR14198; PTHR14198; 1.
DR   Pfam; PF05805; L6_membrane; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..201
FT                   /note="Transmembrane 4 L6 family member 18"
FT                   /id="PRO_0000284969"
FT   TOPO_DOM        1..9
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        31..49
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..93
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        115..157
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        179..201
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  22199 MW;  0CDCCF51AFA7FECF CRC64;
     MGSRKCGSCL SSLLIPLALW SIIVNILLYF PNGQASYASS NKLTNYVWYF EGICFSGIMM
     LVVAAVLLVL ENDNNYKCCQ SENCSKKYMT VLSMIFSALG IAFSGYCLVI SALGLLQGPY
     CRTLDGWEYA FEGTAGRFLT DSREWIQCLE PAHVVEWNII LFSILIALSG LQVIVCLIRV
     VIQLSKSLCG TYSVIIQPGI I