ID   18K2_MYCIT              Reviewed;         140 AA.
AC   P46732;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=18 kDa antigen 2;
DE   AltName: Full=18 kDa antigen clone MINTC541;
OS   Mycobacterium intracellulare.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1767;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 35772 / TMC 1469 / Darden / Serovar 19;
RX   PubMed=8454357; DOI=10.1128/iai.61.4.1509-1515.1993;
RA   Booth R.J., Williams D.L., Moudgil K.D., Noonan L.C., Grandison P.M.,
RA   McKee J.J., Prestidge R.L., Watson J.D.;
RT   "Homologs of Mycobacterium leprae 18-kilodalton and Mycobacterium
RT   tuberculosis 19-kilodalton antigens in other mycobacteria.";
RL   Infect. Immun. 61:1509-1515(1993).
CC   -!- FUNCTION: Not known. This protein is one of the major immune reactive
CC       proteins in mycobacteria.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR   EMBL; L12239; AAA25347.1; -; Genomic_DNA.
DR   RefSeq; WP_008262748.1; NZ_LZIO01000062.1.
DR   AlphaFoldDB; P46732; -.
DR   SMR; P46732; -.
DR   GeneID; 66743068; -.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..140
FT                   /note="18 kDa antigen 2"
FT                   /id="PRO_0000126015"
FT   DOMAIN          21..131
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ   SEQUENCE   140 AA;  15749 MW;  4CCCB07BE235600E CRC64;
     MLVRSDPFRD LDRFTQQLSG TAARPAAMPM DAWRDGEQFV VEFDLPGIDE QSLDLDIERN
     VVTVRAERPD VDPSREMLAT ERARGVFSRQ LVLGDNLDTE HIDACYDAGV LRLRIPVAEK
     AKPRKIAVNR GDRQQTAISA