TAC_TERAN
ID TAC_TERAN Reviewed; 87 AA.
AC P0DN44;
DT 09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT 09-DEC-2015, sequence version 1.
DT 25-MAY-2022, entry version 11.
DE RecName: Full=Tan_10cys {ECO:0000303|PubMed:26025559};
DE Flags: Precursor;
OS Terebra anilis (Auger snail) (Cinguloterebra anilis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Terebra.
OX NCBI_TaxID=553697;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom duct;
RX PubMed=26025559; DOI=10.1093/gbe/evv104;
RA Gorson J., Ramrattan G., Verdes A., Wright E.M., Kantor Y.,
RA Rajaram Srinivasan R., Musunuri R., Packer D., Albano G., Qiu W.G.,
RA Holford M.;
RT "Molecular diversity and gene evolution of the venom arsenal of Terebridae
RT predatory marine snails.";
RL Genome Biol. Evol. 7:1761-1778(2015).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:26025559}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC {ECO:0000305|PubMed:26025559}.
CC -!- DOMAIN: The cysteine framework is C-CC-C-C-C-C-C-C-C.
CC -!- PTM: Contains 5 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the teretoxin C (TC) superfamily.
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DR AlphaFoldDB; P0DN44; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal;
KW Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..27
FT /evidence="ECO:0000305"
FT /id="PRO_0000435052"
FT CHAIN 28..87
FT /note="Tan_10cys"
FT /id="PRO_0000435053"
SQ SEQUENCE 87 AA; 9914 MW; C77F42D8C351FAD7 CRC64;
MNLKVLFLLA MVLVTLCLGE DRVTDRRQLC KCCAKLCHED RDRTIPCSGG NSQFCEFCKR
TKQKIRKDCN TQNEAKALCV GYFTGEC