TADA1_PONAB
ID TADA1_PONAB Reviewed; 335 AA.
AC Q5RDB9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Transcriptional adapter 1;
DE AltName: Full=Transcriptional adapter 1-like protein;
GN Name=TADA1; Synonyms=TADA1L;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in transcriptional regulation.
CC -!- SUBUNIT: Component of the STAGA transcription coactivator-HAT complex,
CC at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L,
CC TAD1L, TAF10, TAF12, TRRAP and TAF9. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TADA1 family. {ECO:0000305}.
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DR EMBL; CR857995; CAH90238.1; -; mRNA.
DR RefSeq; NP_001125101.1; NM_001131629.1.
DR AlphaFoldDB; Q5RDB9; -.
DR SMR; Q5RDB9; -.
DR STRING; 9601.ENSPPYP00000000651; -.
DR Ensembl; ENSPPYT00000000677; ENSPPYP00000000652; ENSPPYG00000000557.
DR GeneID; 100171983; -.
DR KEGG; pon:100171983; -.
DR CTD; 117143; -.
DR eggNOG; ENOG502QRMT; Eukaryota.
DR GeneTree; ENSGT00390000011644; -.
DR InParanoid; Q5RDB9; -.
DR OrthoDB; 1528613at2759; -.
DR Proteomes; UP000001595; Chromosome 1.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005925; C:focal adhesion; IEA:Ensembl.
DR GO; GO:0000124; C:SAGA complex; IEA:Ensembl.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR GO; GO:0043966; P:histone H3 acetylation; IEA:Ensembl.
DR GO; GO:0035522; P:monoubiquitinated histone H2A deubiquitination; IEA:Ensembl.
DR InterPro; IPR024738; Hfi1/Tada1.
DR PANTHER; PTHR21277; PTHR21277; 1.
DR Pfam; PF12767; SAGA-Tad1; 2.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..335
FT /note="Transcriptional adapter 1"
FT /id="PRO_0000316017"
FT REGION 83..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 335 AA; 37382 MW; 1B07D4613107A584 CRC64;
MATFVSELEA AKKNLSEALG DNVKQYWANL KLWFKQKISK EEFDLEAHRL LTQDNVHSHN
DFLLAILTRC QILVSTPDGA GSLPWPGGSA AKPGKPKGKK KLSSVRQKFD HRFQPQNPLS
GAQQFVAKDP QDDDDLKLCS HTMMLPTRGQ LEGRMIVTAY EHGLDNVTEE AVSAVVYAVE
NHLKDILTSV VSRRKAYRLR DGHFKYAFGS NVTPQPYLKN SVVAYNNLIE SPPAFTAPCA
GQNPASHPPP DDAEQQAALL LACSGDTLPA SLPPVNMYDL FEALQVHREV IPTHTVYALN
IERIITKLWH PNHEELQQDK VHRQRLAAKE GLLLC