ID   TADA3_DANRE             Reviewed;         429 AA.
AC   Q7SY21;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Transcriptional adapter 3;
DE   AltName: Full=ADA3 homolog;
DE   AltName: Full=Transcriptional adapter 3-like;
DE            Short=ADA3-like protein;
GN   Name=tada3; Synonyms=ada3, tada3l;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as a component of the PCAF complex. The PCAF
CC       complex is capable of efficiently acetylating histones in a nucleosomal
CC       context (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NGG1 family. {ECO:0000305}.
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DR   EMBL; BC055157; AAH55157.1; -; mRNA.
DR   RefSeq; NP_956220.1; NM_199926.1.
DR   AlphaFoldDB; Q7SY21; -.
DR   SMR; Q7SY21; -.
DR   STRING; 7955.ENSDARP00000075497; -.
DR   PaxDb; Q7SY21; -.
DR   PRIDE; Q7SY21; -.
DR   GeneID; 334785; -.
DR   KEGG; dre:334785; -.
DR   CTD; 334785; -.
DR   ZFIN; ZDB-GENE-030131-6725; tada3l.
DR   eggNOG; KOG4191; Eukaryota.
DR   InParanoid; Q7SY21; -.
DR   OrthoDB; 1026409at2759; -.
DR   PhylomeDB; Q7SY21; -.
DR   Reactome; R-DRE-5689880; Ub-specific processing proteases.
DR   PRO; PR:Q7SY21; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR019340; Histone_AcTrfase_su3.
DR   PANTHER; PTHR13556; PTHR13556; 2.
DR   Pfam; PF10198; Ada3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..429
FT                   /note="Transcriptional adapter 3"
FT                   /id="PRO_0000357454"
FT   REGION          86..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          208..257
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          41..70
FT                   /evidence="ECO:0000255"
FT   COILED          364..404
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        86..110
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..248
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   429 AA;  48908 MW;  524C93FD909EA6CC CRC64;
     MSELKDCPPL KYYDFKPVDH VKVCPRYTAV LSRSEDDGIG IEELDTLQLE LETLLSSASR
     RLRALEEQRQ ILTDWQDKKG DKRFLKLEKD PDLAASSRHS KPKKQKLDVK GSHGPGPGPG
     RPKSKNIQTK VQDFEFEVDP QDIPRNPKND APNRFWASVE PYCADITNEE IRVLEELLKA
     PDDEAEYYKI PTLGKHYSQR WAQEDLLEER REGARANDKK KSMMGPLSEL DAKDVDALLK
     KSESQHEPPE DGCPFGPLSQ RLLQALVEEN IISPMEDSPI PDIPGKDDGA GTSPRSQGKA
     FSVPHTRSLE ARIREELVSQ GLLDSDERQG VGGESEDEVL AELQKRQAEL KALTAHNRSR
     KLELLKLARE EMRKQELRQR VRVADNEVME AFRRIMAARQ KKRTPTKKEK DQAWKALKER
     ESILKLLDG