ID   TADA3_XENTR             Reviewed;         432 AA.
AC   Q66JG5;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Transcriptional adapter 3;
DE   AltName: Full=ADA3 homolog;
DE   AltName: Full=Transcriptional adapter 3-like;
DE            Short=ADA3-like protein;
GN   Name=tada3; Synonyms=ada3, tada3l;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions as a component of the PCAF complex. The PCAF
CC       complex is capable of efficiently acetylating histones in a nucleosomal
CC       context (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NGG1 family. {ECO:0000305}.
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DR   EMBL; BC080923; AAH80923.1; -; mRNA.
DR   RefSeq; NP_001008040.1; NM_001008039.1.
DR   AlphaFoldDB; Q66JG5; -.
DR   SMR; Q66JG5; -.
DR   PaxDb; Q66JG5; -.
DR   DNASU; 493402; -.
DR   Ensembl; ENSXETT00000051085; ENSXETP00000051085; ENSXETG00000023674.
DR   GeneID; 493402; -.
DR   KEGG; xtr:493402; -.
DR   CTD; 10474; -.
DR   Xenbase; XB-GENE-969840; tada3.
DR   eggNOG; KOG4191; Eukaryota.
DR   HOGENOM; CLU_038515_0_0_1; -.
DR   InParanoid; Q66JG5; -.
DR   OrthoDB; 1026409at2759; -.
DR   Reactome; R-XTR-5689880; Ub-specific processing proteases.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000023674; Expressed in 2-cell stage embryo and 12 other tissues.
DR   GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR019340; Histone_AcTrfase_su3.
DR   PANTHER; PTHR13556; PTHR13556; 2.
DR   Pfam; PF10198; Ada3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..432
FT                   /note="Transcriptional adapter 3"
FT                   /id="PRO_0000357455"
FT   REGION          88..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          275..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          40..69
FT                   /evidence="ECO:0000255"
FT   COILED          367..407
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        88..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..309
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   432 AA;  49075 MW;  05B6E4259516DC03 CRC64;
     MSELKDCPLQ FHDFKSVDHV KLCPRYTAVL SRSEDDGIGI EELDTLQLEL ETLLSSASRR
     LRVLEAETQI LTDWQDKKGD RRFLKLGKEH ELGTPIKHSK PKKQKLDGKG SHASGPGPGR
     PKSRNMQQKM QEYEFTDDPV DVPRIPKNDA PNRFWASVEP YCADITNDEI KVLEDLLKTP
     EDEADYYKIP PLGKHYSQRW AQEDLLEEQK DGARTALSGD KKKGILGPLA ELDSKDVDSL
     LKKSESQHDQ PEDGCPFGHL TQRLLQALVE ENIISPVEDS PIPEISGKES GTDGASTSPR
     SQNKPFSAPH TKSLEVRIKE ELIAQGLLES DDRPAEDSED EVLAELRKRQ AELKALSAHN
     RAKKQELLRL AKEEMNRQEL RQRVRMADNE VMDAFRKIMA ARQKKRTPTK KEKDQAWKAL
     KERESILKLL DG