ID   TAF11_PONAB             Reviewed;         211 AA.
AC   Q5RA91;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Transcription initiation factor TFIID subunit 11;
DE   AltName: Full=TFIID subunit p30-beta;
DE   AltName: Full=Transcription initiation factor TFIID 28 kDa subunit;
DE            Short=TAF(II)28;
DE            Short=TAFII-28;
DE            Short=TAFII28;
GN   Name=TAF11;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The TFIID basal transcription factor complex plays a major
CC       role in the initiation of RNA polymerase II (Pol II)-dependent
CC       transcription. TFIID recognizes and binds promoters with or without a
CC       TATA box via its subunit TBP, a TATA-box-binding protein, and promotes
CC       assembly of the pre-initiation complex (PIC). The TFIID complex
CC       consists of TBP and TBP-associated factors (TAFs), including TAF1,
CC       TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and
CC       TAF13. TAF11, together with TAF13 and TBP, play key roles during
CC       promoter binding by the TFIID and TFIIA transcription factor complexes.
CC       {ECO:0000250|UniProtKB:Q15544}.
CC   -!- SUBUNIT: Component of the TFIID basal transcription factor complex,
CC       composed of TATA-box-binding protein TBP, and a number of TBP-
CC       associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5,
CC       TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Interacts with
CC       TAF13 both in vitro and intracellularly; also interacts directly with
CC       TBP. {ECO:0000250|UniProtKB:Q15544}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: TBP and TAFII18 bind to distinct domains of TAFII28.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TAF11 family. {ECO:0000305}.
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DR   EMBL; CR859127; CAH91319.1; -; mRNA.
DR   RefSeq; NP_001127402.1; NM_001133930.2.
DR   AlphaFoldDB; Q5RA91; -.
DR   SMR; Q5RA91; -.
DR   STRING; 9601.ENSPPYP00000018476; -.
DR   GeneID; 100174472; -.
DR   KEGG; pon:100174472; -.
DR   CTD; 6882; -.
DR   eggNOG; KOG3219; Eukaryota.
DR   HOGENOM; CLU_088696_0_0_1; -.
DR   InParanoid; Q5RA91; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IEA:InterPro.
DR   CDD; cd08048; TAF11; 1.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR045127; TAF11-like.
DR   InterPro; IPR006809; TAFII28_dom.
DR   PANTHER; PTHR13218; PTHR13218; 1.
DR   Pfam; PF04719; TAFII28; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..211
FT                   /note="Transcription initiation factor TFIID subunit 11"
FT                   /id="PRO_0000118904"
FT   REGION          1..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..69
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q15544"
SQ   SEQUENCE   211 AA;  23236 MW;  BDA9986848362D4D CRC64;
     MDDAHKSPSD KGGETGESDE TAAAPGDPGA TDTDGIPEDT DGDADADLKE AAAEEGELKS
     QDISDLTTVE REDSSLLTPA AKKLKIDTKE KKEKKQKVDE DEIQKMQILV SSFSEEQLNR
     YEMYRRSAFP KAAIKRLIQS ITGTSVSQNV VIAMSGISKV FVGEVVEEAL DVCEKWGEMP
     PLQPKHMREA VRRLKSKGQI PNSKHKKIIF F