TAF13_ARATH
ID TAF13_ARATH Reviewed; 126 AA.
AC Q6NQH4;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Transcription initiation factor TFIID subunit 13;
DE AltName: Full=TBP-associated factor 13;
DE Short=AtTAF13;
GN Name=TAF13; OrderedLocusNames=At1g02680;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION, NOMENCLATURE, AND TISSUE
RP SPECIFICITY.
RX PubMed=15527982; DOI=10.1016/j.gene.2004.08.023;
RA Lago C., Clerici E., Mizzi L., Colombo L., Kater M.M.;
RT "TBP-associated factors in Arabidopsis.";
RL Gene 342:231-241(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH TAF4B; TAF8; TAF9; TAF10;
RP TAF11; TAF12; TAF12B AND TAF14.
RC STRAIN=cv. Columbia;
RX PubMed=17340043; DOI=10.1007/s11103-007-9135-1;
RA Lawit S.J., O'Grady K., Gurley W.B., Czarnecka-Verner E.;
RT "Yeast two-hybrid map of Arabidopsis TFIID.";
RL Plant Mol. Biol. 64:73-87(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP FUNCTION, INTERACTION WITH MEA AND EZA1, DISRUPTION PHENOTYPE,
RP DEVELOPMENTAL STAGE, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=23506837; DOI=10.1016/j.ydbio.2013.03.005;
RA Lindner M., Simonini S., Kooiker M., Gagliardini V., Somssich M.,
RA Hohenstatt M., Simon R., Grossniklaus U., Kater M.M.;
RT "TAF13 interacts with PRC2 members and is essential for Arabidopsis seed
RT development.";
RL Dev. Biol. 379:28-37(2013).
CC -!- FUNCTION: TAFs are components of the transcription factor IID (TFIID)
CC complex that is essential for mediating regulation of RNA polymerase
CC transcription. May be involved in polycomb repressive complex 2 (PRC2)
CC mediated repression. {ECO:0000269|PubMed:23506837}.
CC -!- SUBUNIT: Component of the TFIID complex. TFIID is composed of TATA
CC binding protein (TBP) and a number of TBP-associated factors (TAFs)
CC whose MWs range from 14-217 kDa. Interacts with TAF4B, TAF8, TAF9,
CC TAF10, TAF11, TAF12, TAF12B and TAF14. Interacts with the members of
CC the polycomb repressive complex 2 (PRC2) MEA and EZA1.
CC {ECO:0000269|PubMed:17340043, ECO:0000269|PubMed:23506837}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23506837}. Cell
CC membrane {ECO:0000269|PubMed:23506837}. Note=At the torpedo stage,
CC localized both in the nucleus and at the plasma membrane.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and inflorescences.
CC {ECO:0000269|PubMed:15527982}.
CC -!- DEVELOPMENTAL STAGE: Detected early after fertilization in the zygotic
CC embryo and free endosperm nuclei. Expression continues in the embryo at
CC the heart and torpedo stages, but is restricted to the chalazal nuclei
CC in endosperm before cellularization. At maturity, expressed mainly in
CC the embryo epidermis and in the vascular tissue.
CC {ECO:0000269|PubMed:23506837}.
CC -!- DISRUPTION PHENOTYPE: Embryo lethal when homozygote.
CC {ECO:0000269|PubMed:23506837}.
CC -!- SIMILARITY: Belongs to the TAF13 family. {ECO:0000305}.
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DR EMBL; AY463615; AAR28017.1; -; mRNA.
DR EMBL; AC022521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE27457.1; -; Genomic_DNA.
DR EMBL; BT010482; AAQ65105.1; -; mRNA.
DR EMBL; AK175906; BAD43669.1; -; mRNA.
DR EMBL; AK175966; BAD43729.1; -; mRNA.
DR EMBL; AK176854; BAD44617.1; -; mRNA.
DR EMBL; AK221393; BAD94327.1; -; mRNA.
DR EMBL; AB493426; BAH30264.1; -; mRNA.
DR RefSeq; NP_171768.2; NM_100148.3.
DR AlphaFoldDB; Q6NQH4; -.
DR SMR; Q6NQH4; -.
DR BioGRID; 23202; 13.
DR IntAct; Q6NQH4; 12.
DR STRING; 3702.AT1G02680.1; -.
DR PaxDb; Q6NQH4; -.
DR PRIDE; Q6NQH4; -.
DR ProteomicsDB; 233006; -.
DR EnsemblPlants; AT1G02680.1; AT1G02680.1; AT1G02680.
DR GeneID; 837962; -.
DR Gramene; AT1G02680.1; AT1G02680.1; AT1G02680.
DR KEGG; ath:AT1G02680; -.
DR Araport; AT1G02680; -.
DR TAIR; locus:2196040; AT1G02680.
DR eggNOG; KOG3901; Eukaryota.
DR HOGENOM; CLU_076665_2_0_1; -.
DR InParanoid; Q6NQH4; -.
DR OMA; INEMCLE; -.
DR OrthoDB; 1478135at2759; -.
DR PhylomeDB; Q6NQH4; -.
DR PRO; PR:Q6NQH4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q6NQH4; baseline and differential.
DR Genevisible; Q6NQH4; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0009960; P:endosperm development; IMP:TAIR.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd07978; TAF13; 1.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR003195; TFIID_TAF13.
DR PANTHER; PTHR11380; PTHR11380; 1.
DR Pfam; PF02269; TFIID-18kDa; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 1: Evidence at protein level;
KW Activator; Cell membrane; Membrane; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..126
FT /note="Transcription initiation factor TFIID subunit 13"
FT /id="PRO_0000424053"
FT DOMAIN 30..74
FT /note="Histone-fold"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 126 AA; 14254 MW; 6FCCE81D08097911 CRC64;
MSNTPAAAAS SSSKSKAAGT SQPQEKRKTL FQKELQHMMY GFGDEQNPLP ESVALVEDIV
VEYVTDLTHK AQEIGSKRGR LLVDDFLYLI RKDLPKLNRC RELLAMQEEL KQARKAFDVD
EKELVD
