ID   TAF13_BOVIN             Reviewed;         124 AA.
AC   Q148M7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Transcription initiation factor TFIID subunit 13 {ECO:0000250|UniProtKB:Q15543};
DE   AltName: Full=Transcription initiation factor TFIID 18 kDa subunit {ECO:0000250|UniProtKB:Q15543};
DE            Short=TAF(II)18 {ECO:0000250|UniProtKB:Q15543};
DE            Short=TAFII-18 {ECO:0000250|UniProtKB:Q15543};
DE            Short=TAFII18 {ECO:0000250|UniProtKB:Q15543};
GN   Name=TAF13 {ECO:0000250|UniProtKB:Q15543};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thymus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The TFIID basal transcription factor complex plays a major
CC       role in the initiation of RNA polymerase II (Pol II)-dependent
CC       transcription. TFIID recognizes and binds promoters via its subunit
CC       TBP, a TATA-box-binding protein, and promotes assembly of the pre-
CC       initiation complex (PIC). The TFIID complex consists of TBP and TBP-
CC       associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5,
CC       TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF13, together
CC       with TAF11 and TBP, play key roles during promoter binding by the TFIID
CC       and TFIIA transcription factor complexes.
CC       {ECO:0000250|UniProtKB:Q15543}.
CC   -!- SUBUNIT: Component of the TFIID basal transcription factor complex,
CC       composed of TATA-box-binding protein TBP, and a number of TBP-
CC       associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5,
CC       TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Interacts with
CC       TBP, and more strongly with TAF10 and TAF11.
CC       {ECO:0000250|UniProtKB:Q15543}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q15543}.
CC   -!- DOMAIN: The binding of TAF10 and TAF11 requires distinct domains of
CC       TAF13. {ECO:0000250|UniProtKB:Q15543}.
CC   -!- SIMILARITY: Belongs to the TAF13 family. {ECO:0000305}.
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DR   EMBL; BC118136; AAI18137.1; -; mRNA.
DR   RefSeq; NP_001069065.1; NM_001075597.1.
DR   AlphaFoldDB; Q148M7; -.
DR   SMR; Q148M7; -.
DR   STRING; 9913.ENSBTAP00000042334; -.
DR   PaxDb; Q148M7; -.
DR   GeneID; 513065; -.
DR   KEGG; bta:513065; -.
DR   CTD; 6884; -.
DR   eggNOG; KOG3901; Eukaryota.
DR   HOGENOM; CLU_076665_4_0_1; -.
DR   InParanoid; Q148M7; -.
DR   OrthoDB; 1478135at2759; -.
DR   TreeFam; TF323609; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd07978; TAF13; 1.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR003195; TFIID_TAF13.
DR   PANTHER; PTHR11380; PTHR11380; 1.
DR   Pfam; PF02269; TFIID-18kDa; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..124
FT                   /note="Transcription initiation factor TFIID subunit 13"
FT                   /id="PRO_0000268198"
FT   DOMAIN          32..74
FT                   /note="Histone-fold"
FT                   /evidence="ECO:0000305"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   124 AA;  14287 MW;  98B62FF1BC8E7B77 CRC64;
     MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL
     VIEFITEMTH KAMSIGRQGR VQVEDIVFLI RKDPRKFARV KDLLTMNEEL KRARKAFDEA
     NYGS