ID   TAF1D_BOVIN             Reviewed;         274 AA.
AC   Q32LB6;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit D;
DE   AltName: Full=TATA box-binding protein-associated factor 1D;
DE            Short=TBP-associated factor 1D;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit D;
GN   Name=TAF1D; Synonyms=JOSD3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the transcription factor SL1/TIF-IB complex,
CC       which is involved in the assembly of the PIC (preinitiation complex)
CC       during RNA polymerase I-dependent transcription. The rate of PIC
CC       formation probably is primarily dependent on the rate of association of
CC       SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
CC       stabilization of nucleolar transcription factor 1/UBTF on rDNA.
CC       Formation of SL1/TIF-IB excludes the association of TBP with TFIID
CC       subunits (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the transcription factor SL1/TIF-IB complex,
CC       composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts
CC       with UBTF (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC109659; AAI09660.1; -; mRNA.
DR   RefSeq; NP_001032675.1; NM_001037586.2.
DR   AlphaFoldDB; Q32LB6; -.
DR   STRING; 9913.ENSBTAP00000004611; -.
DR   PaxDb; Q32LB6; -.
DR   PRIDE; Q32LB6; -.
DR   Ensembl; ENSBTAT00000004611; ENSBTAP00000004611; ENSBTAG00000003545.
DR   GeneID; 505533; -.
DR   KEGG; bta:505533; -.
DR   CTD; 79101; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003545; -.
DR   VGNC; VGNC:35572; TAF1D.
DR   eggNOG; ENOG502SQMW; Eukaryota.
DR   GeneTree; ENSGT00390000009061; -.
DR   HOGENOM; CLU_071614_1_0_1; -.
DR   InParanoid; Q32LB6; -.
DR   OMA; CFIISTE; -.
DR   OrthoDB; 1263117at2759; -.
DR   TreeFam; TF335756; -.
DR   Reactome; R-BTA-5250924; B-WICH complex positively regulates rRNA expression.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000003545; Expressed in pharyngeal tonsil and 109 other tissues.
DR   GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0005668; C:RNA polymerase transcription factor SL1 complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR027976; TAF1D.
DR   PANTHER; PTHR14562; PTHR14562; 1.
DR   Pfam; PF15333; TAF1D; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..274
FT                   /note="TATA box-binding protein-associated factor RNA
FT                   polymerase I subunit D"
FT                   /id="PRO_0000250716"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..32
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..106
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         20
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
FT   MOD_RES         132
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
FT   MOD_RES         229
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
SQ   SEQUENCE   274 AA;  32071 MW;  60EC9F98142DB38C CRC64;
     MDSLNYTTAC DSAVETENQS DNSSSGSSLF KTQCVPVPPK RRQRNTIRKF VHIPKNTQAT
     ESSSDSSIEP RPLTLKAIFE RFKNKKRKRK KKKYKPTGRS VGRPKGRRTT RYSQITEKQF
     KDKRPGFPFL ESENGRKPLP WRKILTFEQA VARGFFNYLE KLKYEYYLKE SLKQMNVAED
     LEKDDLDSRR YRYLDDDGSL SPIEESAAEE ETAANLEHDE CDIKLVENSY FIISSEFPKK
     KQNVHLDQEE YTEETALLKK RTSKSKHWIE DKMA