ID   TAF1D_PONAB             Reviewed;         278 AA.
AC   Q5RCX3;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit D;
DE   AltName: Full=TATA box-binding protein-associated factor 1D;
DE            Short=TBP-associated factor 1D;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit D;
GN   Name=TAF1D; Synonyms=JOSD3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the transcription factor SL1/TIF-IB complex,
CC       which is involved in the assembly of the PIC (preinitiation complex)
CC       during RNA polymerase I-dependent transcription. The rate of PIC
CC       formation probably is primarily dependent on the rate of association of
CC       SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in
CC       stabilization of nucleolar transcription factor 1/UBTF on rDNA.
CC       Formation of SL1/TIF-IB excludes the association of TBP with TFIID
CC       subunits (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the transcription factor SL1/TIF-IB complex,
CC       composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts
CC       with UBTF (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CR858145; CAH90384.1; -; mRNA.
DR   RefSeq; NP_001128983.1; NM_001135511.2.
DR   AlphaFoldDB; Q5RCX3; -.
DR   STRING; 9601.ENSPPYP00000004318; -.
DR   GeneID; 100190823; -.
DR   KEGG; pon:100190823; -.
DR   CTD; 79101; -.
DR   eggNOG; ENOG502SQMW; Eukaryota.
DR   InParanoid; Q5RCX3; -.
DR   OrthoDB; 1263117at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005668; C:RNA polymerase transcription factor SL1 complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR027976; TAF1D.
DR   PANTHER; PTHR14562; PTHR14562; 1.
DR   Pfam; PF15333; TAF1D; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..278
FT                   /note="TATA box-binding protein-associated factor RNA
FT                   polymerase I subunit D"
FT                   /id="PRO_0000250719"
FT   REGION          19..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          88..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..57
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..102
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         23
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
FT   MOD_RES         138
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
FT   MOD_RES         234
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H5J8"
SQ   SEQUENCE   278 AA;  32242 MW;  DEA2E9A1D8294B91 CRC64;
     MDKSGIDSLD HVTSDAVELA NRSDNSSDSR LFKTQCIPYS PKREKRNPIR KFVRTPESVH
     ASDSSSDSSF EPIPLTMKAI FERFKNRKKR YKKKKKKRYQ PTGRPRGRPE GRRNPIYSLI
     DKKKQFRSRG SGFPFLESEN EKNPPWRKIL TFEQAVARGF FNYIEKLKYE HHLKESLKQM
     NVGEDLENED FDSRRYKFLD DDGSISPIEE STAEDEDATH LEDNECDIKL AGDSFIVSSE
     FPVRLSVYLE EEDITEEAAL SKKRATKAKN TGQRGLKM