ID   TAF2_CHICK              Reviewed;        1168 AA.
AC   Q5ZIT8;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Transcription initiation factor TFIID subunit 2;
DE   AltName: Full=TBP-associated factor 150 kDa;
DE   AltName: Full=Transcription initiation factor TFIID 150 kDa subunit;
DE            Short=TAF(II)150;
DE            Short=TAFII-150;
DE            Short=TAFII150;
GN   Name=TAF2; ORFNames=RCJMB04_23j21;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: The TFIID basal transcription factor complex plays a major
CC       role in the initiation of RNA polymerase II (Pol II)-dependent
CC       transcription. TFIID recognizes and binds promoters with or without a
CC       TATA box via its subunit TBP, a TATA-box-binding protein, and promotes
CC       assembly of the pre-initiation complex (PIC). The TFIID complex
CC       consists of TBP and TBP-associated factors (TAFs).
CC       {ECO:0000250|UniProtKB:Q6P1X5}.
CC   -!- SUBUNIT: Component of the TFIID basal transcription factor complex,
CC       composed of TATA-box-binding protein TBP, and a number of TBP-
CC       associated factors (TAFs). {ECO:0000250|UniProtKB:Q6P1X5}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TAF2 family. {ECO:0000305}.
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DR   EMBL; AJ720696; CAG32355.1; -; mRNA.
DR   RefSeq; NP_001292091.1; NM_001305162.1.
DR   AlphaFoldDB; Q5ZIT8; -.
DR   SMR; Q5ZIT8; -.
DR   STRING; 9031.ENSGALP00000026442; -.
DR   MEROPS; M01.972; -.
DR   GeneID; 428389; -.
DR   KEGG; gga:428389; -.
DR   CTD; 6873; -.
DR   VEuPathDB; HostDB:geneid_428389; -.
DR   eggNOG; KOG1932; Eukaryota.
DR   InParanoid; Q5ZIT8; -.
DR   OrthoDB; 142542at2759; -.
DR   PhylomeDB; Q5ZIT8; -.
DR   PRO; PR:Q5ZIT8; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR   GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:GO_Central.
DR   Gene3D; 1.10.390.10; -; 1.
DR   Gene3D; 2.60.40.1730; -; 1.
DR   InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR037813; TAF2.
DR   PANTHER; PTHR15137; PTHR15137; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF63737; SSF63737; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..1168
FT                   /note="Transcription initiation factor TFIID subunit 2"
FT                   /id="PRO_0000252426"
FT   REGION          1039..1066
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1135..1168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1143..1168
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1168 AA;  134023 MW;  6D88FA73F8541BAD CRC64;
     MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGYVE LTIFPTVANL NRIKLNSKQC
     RIYRVRVNDL EAAFIYNDPT LEVCHHESKQ RNLNYFSNAY AAAVSAVDPD AGNGELCIKV
     PSELWKHVDE LKVLKVHINF SLDQPKGGLH FVVPNMEGSM AERGAHVFSC GYQNSTRFWF
     PCVDSYSELC TWKLEYTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLAI PTAASNISLA
     IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYLHEVFEF YEEILTCRYP YSCFKTVFID
     EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQAL AQQFFGCFIS RMSWSDEWVL
     KGISGYIYGL WMKKTFGVNE YRHWIKQELD QIVAYELKTG GVLLHPIFGG GKEKDNPASH
     LHFSIKHPHT LSWEYYTMFQ CKAHLVMRLI ENRISMEFML QVFNKLLSLA STASSQKFQS
     HMWSQMLVST SGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK RNVLELEIKQ
     DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK KKKIPLMNGE
     EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQSDFMWQ YQLRYERDVV AQEEAILALE
     KFPTPASRLA LTDILEQEQC FYRVRMLACF CLAKIANSMV STWTGPPAMK SLFTRMFCCK
     TCPNIVKTNN FMNFQSYFLQ KTMPVAMALL RDVHNLCPKE VLMFILDLIK YNDNRKNKFS
     DNYYRAELID ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME KLLPSYRHTI
     TVSCLKAIRV LQKNGHVPSD PALFKSYAEY GHFVDVRIAA LEAVVDYTKV DRSYEELQWL
     LTMVQNDPVP YIRHKILDML TKNPPFTKNM ESPLCNEALV DQLWKLMNSG TSHDWRLRCG
     AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE KKAVLNPTII PESVANNQEP VNTTNNHGQP
     VVFQNTEDDH LIKETASSIS GHQQGVKRKA DMPLGSPLEP GQILEKNEDS KVKLKIRFSN
     SQEEEEIDMD TVHDSQAFIY HHLNMLERPS TPGKEQSSGE VTMHPVSAAP LSVFSKESNS
     SKHSDHHHHH HHEHKKKKKK TLQVWIRP