TAF5_ARATH
ID TAF5_ARATH Reviewed; 669 AA.
AC Q6S7B0;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 137.
DE RecName: Full=Transcription initiation factor TFIID subunit 5;
DE AltName: Full=TBP-associated factor 5;
DE Short=AtTAF5;
GN Name=TAF5; OrderedLocusNames=At5g25150; ORFNames=F21J6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION, NOMENCLATURE, AND TISSUE
RP SPECIFICITY.
RX PubMed=15527982; DOI=10.1016/j.gene.2004.08.023;
RA Lago C., Clerici E., Mizzi L., Colombo L., Kater M.M.;
RT "TBP-associated factors in Arabidopsis.";
RL Gene 342:231-241(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBUNIT, AND INTERACTION WITH TAF4; TAF4B;
RP TAF6B; TAF8; TAF9; TAF12B; TAF14 AND TAF15B.
RX PubMed=17340043; DOI=10.1007/s11103-007-9135-1;
RA Lawit S.J., O'Grady K., Gurley W.B., Czarnecka-Verner E.;
RT "Yeast two-hybrid map of Arabidopsis TFIID.";
RL Plant Mol. Biol. 64:73-87(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: TAFs are components of the transcription factor IID (TFIID)
CC complex that is essential for mediating regulation of RNA polymerase
CC transcription. {ECO:0000250}.
CC -!- SUBUNIT: Component of the TFIID complexe. TFIID is composed of TATA
CC binding protein (TBP) and a number of TBP-associated factors (TAFs)
CC whose MWs range from 14-217 kDa. May homodimerize to form the scaffold
CC for the complex. Interacts with TAF4, TAF4B, TAF6B, TAF8, TAF9, TAF12B,
CC TAF14 and TAF15B. {ECO:0000269|PubMed:17340043}.
CC -!- INTERACTION:
CC Q6S7B0; F4HVA6: TAF6B; NbExp=3; IntAct=EBI-1247501, EBI-1245557;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and inflorescences.
CC {ECO:0000269|PubMed:15527982}.
CC -!- SIMILARITY: Belongs to the TAF5 family. {ECO:0000305}.
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DR EMBL; AY463620; AAR28022.1; -; mRNA.
DR EMBL; AC006259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93406.1; -; Genomic_DNA.
DR RefSeq; NP_197897.3; NM_122424.4.
DR AlphaFoldDB; Q6S7B0; -.
DR SMR; Q6S7B0; -.
DR BioGRID; 17861; 23.
DR IntAct; Q6S7B0; 12.
DR STRING; 3702.AT5G25150.1; -.
DR iPTMnet; Q6S7B0; -.
DR PaxDb; Q6S7B0; -.
DR PRIDE; Q6S7B0; -.
DR ProteomicsDB; 233007; -.
DR EnsemblPlants; AT5G25150.1; AT5G25150.1; AT5G25150.
DR GeneID; 832586; -.
DR Gramene; AT5G25150.1; AT5G25150.1; AT5G25150.
DR KEGG; ath:AT5G25150; -.
DR Araport; AT5G25150; -.
DR TAIR; locus:2179300; AT5G25150.
DR eggNOG; KOG0263; Eukaryota.
DR HOGENOM; CLU_005884_2_1_1; -.
DR InParanoid; Q6S7B0; -.
DR OMA; RCAFAPE; -.
DR OrthoDB; 620721at2759; -.
DR PhylomeDB; Q6S7B0; -.
DR PRO; PR:Q6S7B0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6S7B0; baseline and differential.
DR Genevisible; Q6S7B0; AT.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:GO_Central.
DR CDD; cd08044; TAF5_NTD2; 1.
DR Gene3D; 1.25.40.500; -; 1.
DR Gene3D; 2.130.10.10; -; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR037783; Taf5.
DR InterPro; IPR007582; TFIID_NTD2.
DR InterPro; IPR037264; TFIID_NTD2_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19879; PTHR19879; 1.
DR Pfam; PF04494; TFIID_NTD2; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF160897; SSF160897; 1.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 1: Evidence at protein level;
KW Activator; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; WD repeat.
FT CHAIN 1..669
FT /note="Transcription initiation factor TFIID subunit 5"
FT /id="PRO_0000424038"
FT REPEAT 350..389
FT /note="WD 1"
FT REPEAT 416..455
FT /note="WD 2"
FT REPEAT 458..497
FT /note="WD 3"
FT REPEAT 500..541
FT /note="WD 4"
FT REPEAT 543..581
FT /note="WD 5"
FT REPEAT 584..623
FT /note="WD 6"
FT REGION 244..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 669 AA; 74414 MW; 0CFC6ED981CD85C7 CRC64;
MDPEQINEFV VGYLKKKGFS SAAKDLESYH HQNNNGSSFT SVDYHNDPEL TKLIRSFSQQ
EDDPTRYREG YSKLRSWAYN SLDLYKHELL RVMYPVFIHC YMDLVGKGHT QEARAFFNSF
RKDHEMVHLR DLQKLEGVLS PSHLEEMEFA RSLRKSKVNI KFCQYSYELL LQYLHSTVST
LMLGIINEHI NFQVYSGQPT SSSDDIEAVT IVGSFQDTAN HINQKEIQWG LLEDSLEDRL
EKTGGLLSDS EKGQGESKDG DADDSKKRST EIGKQGSSLK KLKKDKAGNA TAKVARLETI
TVSPAPRVKP ELALPVMSTD VEQSILEDLR NRVQLSSVAM PSVSFYTFVN THNGLNCSSI
SHDGSLVAGG FSDSSIKVWD MAKIGQAGSG ALQAENDSSD QSIGPNGRRS YTLLLGHSGP
VYSATFSPPG DFVLSSSADT TIRLWSTKLN ANLVCYKGHN YPVWDAQFSP FGHYFASCSH
DRTARIWSMD RIQPLRIMAG HLSDVDCVQW HPNCNYIATG SSDKTVRLWD VQTGECVRIF
IGHRSMVLSL AMSPDGRYMA SGDEDGTIMM WDLSTARCIT PLMGHNSCVW SLSYSGEGSL
LASGSADCTV KLWDVTSSTK LTKAEEKNGN SNRLRSLRTF PTKSTPVHAL RFSRRNLLFA
AGAISKPAN
