ID   TAGH_ENTFA              Reviewed;         447 AA.
AC   Q831L8;
DT   29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Teichoic acids export ATP-binding protein TagH {ECO:0000255|HAMAP-Rule:MF_01715};
DE            EC=7.5.2.4 {ECO:0000255|HAMAP-Rule:MF_01715};
GN   Name=tagH {ECO:0000255|HAMAP-Rule:MF_01715}; OrderedLocusNames=EF_2486;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- FUNCTION: Part of the ABC transporter complex TagGH involved in
CC       teichoic acids export. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01715}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + teichoic acidSide 1 = ADP + phosphate + teichoic
CC         acidSide 2.; EC=7.5.2.4; Evidence={ECO:0000255|HAMAP-Rule:MF_01715};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (TagH) and
CC       two transmembrane proteins (TagG). {ECO:0000255|HAMAP-Rule:MF_01715}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01715};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01715}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Teichoic acids
CC       exporter (TC 3.A.1.104.1) family. {ECO:0000255|HAMAP-Rule:MF_01715}.
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DR   EMBL; AE016830; AAO82202.1; -; Genomic_DNA.
DR   RefSeq; NP_816132.1; NC_004668.1.
DR   RefSeq; WP_010706558.1; NC_004668.1.
DR   AlphaFoldDB; Q831L8; -.
DR   SMR; Q831L8; -.
DR   STRING; 226185.EF_2486; -.
DR   EnsemblBacteria; AAO82202; AAO82202; EF_2486.
DR   KEGG; efa:EF2486; -.
DR   PATRIC; fig|226185.45.peg.1062; -.
DR   eggNOG; COG1134; Bacteria.
DR   eggNOG; COG1388; Bacteria.
DR   HOGENOM; CLU_000604_101_8_9; -.
DR   OMA; RRDEPRM; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015438; F:ABC-type teichoic acid transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03220; ABC_KpsT_Wzt; 1.
DR   CDD; cd00118; LysM; 1.
DR   Gene3D; 3.10.350.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015860; ABC_transpr_TagH-like.
DR   InterPro; IPR018392; LysM_dom.
DR   InterPro; IPR036779; LysM_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF01476; LysM; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00257; LysM; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54106; SSF54106; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51782; LYSM; 1.
DR   PROSITE; PS51251; TAGH; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Translocase; Transport.
FT   CHAIN           1..447
FT                   /note="Teichoic acids export ATP-binding protein TagH"
FT                   /id="PRO_0000092989"
FT   DOMAIN          24..246
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01715"
FT   DOMAIN          398..442
FT                   /note="LysM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT   REGION          247..447
FT                   /note="Unknown"
FT   REGION          359..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..393
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         60..67
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01715"
SQ   SEQUENCE   447 AA;  50100 MW;  C9A1C0003573581C CRC64;
     MEKELKVRTK LLTKEYSLAQ TRIDKLKTLF SVFQNKVPTF WALKGVSLDV YSGETIGIIG
     LNGSGKSTLS NIISGITPQT SGELEINGEV SIISIGAGLN NNLTGRENIR MKCLMLGEKN
     KEIDAKIDDI IEFSELGVFI DQPVKTYSSG MRAKLGFSIA VHQNPDILVI DEALSVGDQT
     FYNKGLKKML AFKEQGKTIF FVSHSIQQVE QICDRVAWMH YGDLRAFGET KHILKEYRAF
     LHRYNHFTEP QKESYQRDGK AKQRNFSLEQ LQETILEKAN QQVGSRRTTK EVIKFTTKNK
     IGDKMTLGTK SLLILLLCMI FYVSLTFVKG ISLTTAFIHP AETIQRIFVP EKVAGKDTNA
     VKTTKTKPAS TKESRQQEEV QPSPTNVPEN NNSEQAVSTY TVEVGDSVSL IAENHGLTIE
     QLQTLNPEII EVPIYPGQVL KLKEVTE