ID   TAL2_NOSP7              Reviewed;         381 AA.
AC   P48983; B2J6J8;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Transaldolase 2;
DE            EC=2.2.1.2;
GN   Name=tal2; OrderedLocusNames=Npun_F4024;
OS   Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=63737;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7870816; DOI=10.1104/pp.107.1.267;
RA   Summers M.L., Meeks J.C., Chu S., Wolf R.E. Jr.;
RT   "Nucleotide sequence of an operon in Nostoc sp. strain ATCC 29133 encoding
RT   four genes of the oxidative pentose phosphate cycle.";
RL   Plant Physiol. 107:267-268(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29133 / PCC 73102;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA   Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT   "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transaldolase is important for the balance of metabolites in
CC       the pentose-phosphate pathway.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate =
CC         beta-D-fructose 6-phosphate + D-erythrose 4-phosphate;
CC         Xref=Rhea:RHEA:17053, ChEBI:CHEBI:16897, ChEBI:CHEBI:57483,
CC         ChEBI:CHEBI:57634, ChEBI:CHEBI:59776; EC=2.2.1.2;
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-
CC       ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage):
CC       step 2/3.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the transaldolase family. Type 2 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; L32796; AAA50769.1; -; Genomic_DNA.
DR   EMBL; CP001037; ACC82403.1; -; Genomic_DNA.
DR   RefSeq; WP_012410370.1; NC_010628.1.
DR   AlphaFoldDB; P48983; -.
DR   SMR; P48983; -.
DR   STRING; 63737.Npun_F4024; -.
DR   EnsemblBacteria; ACC82403; ACC82403; Npun_F4024.
DR   KEGG; npu:Npun_F4024; -.
DR   eggNOG; COG0176; Bacteria.
DR   HOGENOM; CLU_050771_1_0_3; -.
DR   OMA; ATECYYQ; -.
DR   OrthoDB; 417261at2; -.
DR   PhylomeDB; P48983; -.
DR   UniPathway; UPA00115; UER00414.
DR   Proteomes; UP000001191; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004801; F:transaldolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniRule.
DR   CDD; cd00955; Transaldolase_like; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00493; Transaldolase_2; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001585; TAL/FSA.
DR   InterPro; IPR004732; Transaldolase_2.
DR   InterPro; IPR018225; Transaldolase_AS.
DR   PANTHER; PTHR10683; PTHR10683; 1.
DR   Pfam; PF00923; TAL_FSA; 1.
DR   PIRSF; PIRSF036915; Trnald_Bac_Plnt; 1.
DR   TIGRFAMs; TIGR00876; tal_mycobact; 1.
DR   PROSITE; PS01054; TRANSALDOLASE_1; 1.
DR   PROSITE; PS00958; TRANSALDOLASE_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Pentose shunt; Reference proteome; Schiff base; Transferase.
FT   CHAIN           1..381
FT                   /note="Transaldolase 2"
FT                   /id="PRO_0000173629"
FT   ACT_SITE        141
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   381 AA;  42303 MW;  906E28CDE77755F9 CRC64;
     MSTNHLLEIK QYGQSIWMDN LTRDIIQSGE LKDMVENQGI SGITSNPAIF EKAIAGNAIY
     DADIEAGVRA GLPIYKIYES LVFADIRNAC DILRPVYEAS NRLDGYVSIE VPPTIAHDTE
     ATISEARRYF QEIGRENLMI KIPGTEPGLP AVEQVIAEGM NVNITLLFSV ESYVNTAWAY
     VRGLEKRLAE GKDISRIASV ASFFLSRIDS NIDAKIDAKL KKGVDDIAVE AKLKAVKGKV
     AIANAKLAYQ EYKKIIRSER WQELVAKGAT VQRLLWASTS TKDPNYNDVM YIEELVGPDT
     VNTVPPATIK ACADHCNVSD RLETDVNNAY TLIENLKDPD INIDLDTVMD ELLVEGIDKF
     IQPFQSLMNS LEDKIKVLSP V