ID   TAP25_BPMD2             Reviewed;         274 AA.
AC   O64219;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   11-NOV-2015, sequence version 2.
DT   23-FEB-2022, entry version 57.
DE   RecName: Full=Tail assembly protein Gp25 {ECO:0000250|UniProtKB:Q05232};
DE   AltName: Full=Gene 25 protein;
DE   AltName: Full=Gp25;
GN   Name=25;
OS   Mycobacterium phage D29 (Mycobacteriophage D29).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Fromanvirus.
OX   NCBI_TaxID=28369;
OH   NCBI_TaxID=1763; Mycobacterium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9636706; DOI=10.1006/jmbi.1997.1610;
RA   Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F.;
RT   "Genome structure of mycobacteriophage D29: implications for phage
RT   evolution.";
RL   J. Mol. Biol. 279:143-164(1998).
CC   -!- FUNCTION: Promotes tail assembly by creating a scaffold for the tail
CC       tube proteins. The tail assembly proteins Gp24 and Gp25 would wrap the
CC       linear tape measure protein to create a tail assembly scaffold. It
CC       would allow polymerization of tail tube protein during which Gp24 and
CC       Gp25 are released and therefore are absent from the mature virion. The
CC       tail assembly protein Gp25 is produced by a rare -1 ribosomal
CC       frameshift. The ratio Gp24/Gp25 is important for proper tail assembly.
CC       {ECO:0000250|UniProtKB:P03734}.
CC   -!- SUBUNIT: Interacts with tail assembly protein Gp24 and tape measure
CC       protein. {ECO:0000250|UniProtKB:P03734}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=Tail assembly protein Gp25;
CC         IsoId=O64219-1; Sequence=Displayed;
CC       Name=Tail assembly protein Gp24;
CC         IsoId=O64218-1; Sequence=External;
CC   -!- MISCELLANEOUS: [Isoform Tail assembly protein Gp25]: Produced by -1
CC       ribosomal frameshifting.
CC   -!- SIMILARITY: Belongs to the L5likevirus tail assembly protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC18466.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AF022214; AAC18466.1; ALT_SEQ; Genomic_DNA.
DR   PIR; G72802; G72802.
DR   RefSeq; NP_046841.1; NC_001900.1.
DR   PRIDE; O64219; -.
DR   GeneID; 1261587; -.
DR   KEGG; vg:1261587; -.
DR   Proteomes; UP000002131; Genome.
DR   GO; GO:0098003; P:viral tail assembly; IEA:UniProtKB-KW.
DR   InterPro; IPR020132; Gp24/Gp25.
DR   Pfam; PF17388; GP24_25; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribosomal frameshifting; Viral release from host cell;
KW   Viral tail assembly.
FT   CHAIN           1..274
FT                   /note="Tail assembly protein Gp25"
FT                   /id="PRO_0000164738"
FT   REGION          221..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        221..244
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   274 AA;  31102 MW;  E9E49C9E60BCCD47 CRC64;
     MTNVFTIDAF REEVKKKYEP VTIGISEDVT VELKPLLKLG QKAREAVVEA VKEVEDIPDI
     DEDDEEAEEL VDEYSLRICE IVAKVFRLIA TKPKKLIAAL DEEEDPRIRA ELYATVLRTW
     MVETQLGESR ALAELIDKFG GAILSDLSEY HGVDLRDLFR DEDPLSPRYV LNLVIHLPKT
     GAFYAERRGG QQYRGWDEDR YALADIYDAV QAGNHILLMA NRDPKKPKPK APKAYPRPDD
     FEKTTPKPGS FAAMVVAAKK AAREKREREE ANAE