ID   AC109_NPVAC             Reviewed;         390 AA.
AC   P41662;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   29-SEP-2021, entry version 45.
DE   RecName: Full=Protein AC109;
GN   Name=ORF109;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=23049963; DOI=10.1371/journal.pone.0046146;
RA   Alfonso V., Maroniche G.A., Reca S.R., Lopez M.G., del Vas M., Taboga O.;
RT   "AcMNPV core gene ac109 is required for budded virion transport to the
RT   nucleus and for occlusion of viral progeny.";
RL   PLoS ONE 7:E46146-E46146(2012).
RN   [3]
RP   FUNCTION.
RX   PubMed=23149091; DOI=10.1016/j.virol.2012.10.015;
RA   Lehiy C.J., Wu W., Berretta M.F., Passarelli A.L.;
RT   "Autographa californica M nucleopolyhedrovirus open reading frame 109
RT   affects infectious budded virus production and nucleocapsid envelopment in
RT   the nucleus of cells.";
RL   Virology 435:442-452(2013).
CC   -!- FUNCTION: Plays a role in the transport of the budded virion (BV) to
CC       the host nucleus and for occlusion of viral progeny.
CC       {ECO:0000269|PubMed:23049963, ECO:0000269|PubMed:23149091}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:23049963}.
CC       Host nucleus {ECO:0000269|PubMed:23049963}.
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DR   EMBL; L22858; AAA66739.1; -; Genomic_DNA.
DR   PIR; F72863; F72863.
DR   RefSeq; NP_054139.1; NC_001623.1.
DR   GeneID; 1403942; -.
DR   KEGG; vg:1403942; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IDA:UniProtKB.
DR   GO; GO:0042025; C:host cell nucleus; IDA:UniProtKB.
DR   GO; GO:0039708; P:nuclear capsid assembly; IMP:CACAO.
DR   GO; GO:0075606; P:transport of viral material towards nucleus; IDA:UniProtKB.
DR   InterPro; IPR007748; AcMNPV_Orf109.
DR   Pfam; PF05054; AcMNPV_Ac109; 1.
PE   4: Predicted;
KW   Host cytoplasm; Host nucleus; Reference proteome.
FT   CHAIN           1..390
FT                   /note="Protein AC109"
FT                   /id="PRO_0000133043"
SQ   SEQUENCE   390 AA;  44803 MW;  8B8633E21B0AE275 CRC64;
     MECPFQIQVC ISDRFFAFPH NLVEPQSDVG NKLIENLIVY VPTDDDRLYI DKKQFPKFNS
     VLVYRHEHDV NIDSRSPKKT ASATIVYWNP LVPITEIGAG ETRVFSVLLT NNLFYCNTMI
     VHHENPKCPI EFTYPETDMQ SACSALLKNR NGQSVPPPIK SNLRPIACEI PLSHFKELVE
     SNDFLLCFNL ETSTMVKILS LKRIFCIFQY RKQPARYVIN LPHEEIDNLY NKLNWERTRR
     LMKGDVPSNC ATVNRSSLKY IKQAQSLLGI PDYSQTVVDF VKMFQKIIFP YQLVPNVIIK
     LNNFDQMVSS APNKAEPYKK IRLFCKNDSI AISSSGIVPI NMPDFSPPNT FDYSDYANRT
     NINFVTQRVL TDGGFSSGIT VTPVKYNYYL