TAPC_AERHY
ID TAPC_AERHY Reviewed; 413 AA.
AC P45793;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Type IV pilus assembly protein TapC;
GN Name=tapC;
OS Aeromonas hydrophila.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=644;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Ah65;
RX PubMed=8820654; DOI=10.1046/j.1365-2958.1996.431958.x;
RA Pepe C.M., Eklund M.W., Strom M.S.;
RT "Cloning of an Aeromonas hydrophila type IV pilus biogenesis gene cluster:
RT complementation of pilus assembly functions and characterization of a type
RT IV leader peptidase/N-methyltransferase required for extracellular protein
RT secretion.";
RL Mol. Microbiol. 19:857-869(1996).
CC -!- FUNCTION: Involved in the translocation of the type IV pilin.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GSP F family. {ECO:0000305}.
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DR EMBL; U20255; AAC43997.1; -; Genomic_DNA.
DR PIR; S70874; S70874.
DR AlphaFoldDB; P45793; -.
DR SMR; P45793; -.
DR STRING; 1448139.AI20_21740; -.
DR eggNOG; COG1459; Bacteria.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 1.20.81.30; -; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR PANTHER; PTHR30012; PTHR30012; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Fimbrium biogenesis; Membrane;
KW Protein transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..413
FT /note="Type IV pilus assembly protein TapC"
FT /id="PRO_0000207843"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 413 AA; 45386 MW; A5EA2CF03EF90F86 CRC64;
MATLTQKQNA PKKVFAFRWS GVNRKGQKVS GELQADSINT VKAELRKQGV NVTKVSKKSQ
GLFSKGGAKI KPMDIAIVSR QITTMLSAGV PLVQSLQIIA RSHEKASMRE LMGQIAADVE
TGTPMSEALR RHPRHFDALY CDLVEAGEQS GALETIYDRI ATYREKSEAL KSKIKKAMFY
PAMVILVAIV VTSILLLFVI PQFEDIFKSF GAELPIFTQF VIGISRFMQH WWYVIFGGTA
FAIFLYVRAW RASQKVKDNT DKFILTIPVV GMILHKAAMA RFARTLSTTF SAGIPLVDAL
ISAAGASGNY VYRTAVMAIR NEVVAGMQIN VAMRTVDLFP DMVIQMVMIG EESGAIDDML
SKVATIFEQE VDDLVDGLTS LLEPLIMVVL GVLVGGMVVA MYLPIFKLGD LVG