ID   TAPT1_CAEEL             Reviewed;         712 AA.
AC   Q9U3H8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Protein TAPT1 homolog;
GN   ORFNames=F26F2.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TAPT1 family. {ECO:0000305}.
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DR   EMBL; Z81514; CAB62802.1; -; Genomic_DNA.
DR   RefSeq; NP_507972.1; NM_075571.4.
DR   AlphaFoldDB; Q9U3H8; -.
DR   STRING; 6239.F26F2.7; -.
DR   EPD; Q9U3H8; -.
DR   PaxDb; Q9U3H8; -.
DR   PeptideAtlas; Q9U3H8; -.
DR   EnsemblMetazoa; F26F2.7a.1; F26F2.7a.1; WBGene00009172.
DR   GeneID; 180347; -.
DR   UCSC; F26F2.7; c. elegans.
DR   CTD; 180347; -.
DR   WormBase; F26F2.7a; CE19819; WBGene00009172; -.
DR   eggNOG; KOG2490; Eukaryota.
DR   GeneTree; ENSGT00390000010628; -.
DR   HOGENOM; CLU_361018_0_0_1; -.
DR   InParanoid; Q9U3H8; -.
DR   OMA; SIMIIRV; -.
DR   OrthoDB; 342390at2759; -.
DR   PhylomeDB; Q9U3H8; -.
DR   PRO; PR:Q9U3H8; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00009172; Expressed in adult organism and 4 other tissues.
DR   ExpressionAtlas; Q9U3H8; baseline and differential.
DR   GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0035437; P:maintenance of protein localization in endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0045724; P:positive regulation of cilium assembly; IBA:GO_Central.
DR   InterPro; IPR008010; Tatp1.
DR   PANTHER; PTHR13317; PTHR13317; 1.
DR   Pfam; PF05346; DUF747; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..712
FT                   /note="Protein TAPT1 homolog"
FT                   /id="PRO_0000328877"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        402..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        470..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        497..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          44..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          596..712
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        597..638
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        651..695
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   712 AA;  80712 MW;  F8F4703061029797 CRC64;
     MNNVPSTSRE NSRNPSESSS SIQDLLINVE ANDLSSVVNE DVSITMSAPP SPATPRKIDF
     SAEIETPKST GIRRRLTLKD SIGSDLENDP ESTPAIRKPS RISYDERLTV ICDSQTSSPL
     QTPSPSQERD SAPFADVFQP KGFFSFFWEE LTRGYSLHND HARFSEKRRK VYAFLRIPLE
     LEQFLTYGLL QCIDAFFYLF TFLPLRFLMS IFGALLRIKR WTSAETCDFL KVVIIVAASM
     LIREIDSSFL YHQVRSQGVI KLYIFYNMLE VADRLFSSLG QDIFDALLWT ANSEKRFSVG
     YFIRTCGHLI VAILYATLHS FLVILQATTL NVAFNSHNQT VLAIMMSNNF VELKGSVFKK
     FAKANLFQMA CSDVRERFHI FALLFVVMIR NMTAVNWNID SFTEMIPDII MVVGCEYFVD
     WLKHAFITKF NEINAEVYKD FTITIAFDVI RSRDQSAFSD YSDQVSRRMG FIPIPLSIMI
     IRVLSQTFTL DNWGSCIIFG IGWLLVFAVK ICNGVVMLGQ ACHHVKRFRD IQARAEFELF
     RKRMVEKKSK SAPNSPRMSL IDFTDVLHQP AAGKGFTVSD MLSQWEELQP SLLSSEIRRS
     TDRETAVSHL TARSDERTPR RAVSMAHIPR RDRSEPPPAP SMDQDPQLDT EDPVVTENNT
     NSNSEQASPV KKKTTAAPVT SSASTNTNAT SSDELADVTA YKMPEQGVQR IE