ID   TAPT1_DICDI             Reviewed;         828 AA.
AC   Q550C1; Q86K85;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 2.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Protein TAPT1 homolog;
GN   ORFNames=DDB_G0277313;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TAPT1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL68843.2; -; Genomic_DNA.
DR   RefSeq; XP_642695.2; XM_637603.2.
DR   AlphaFoldDB; Q550C1; -.
DR   STRING; 44689.DDB0304431; -.
DR   PaxDb; Q550C1; -.
DR   PRIDE; Q550C1; -.
DR   EnsemblProtists; EAL68843; EAL68843; DDB_G0277313.
DR   GeneID; 8620885; -.
DR   KEGG; ddi:DDB_G0277313; -.
DR   dictyBase; DDB_G0277313; -.
DR   eggNOG; KOG2490; Eukaryota.
DR   HOGENOM; CLU_342381_0_0_1; -.
DR   InParanoid; Q550C1; -.
DR   OMA; NFTESSW; -.
DR   PRO; PR:Q550C1; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0035437; P:maintenance of protein localization in endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR008010; Tatp1.
DR   PANTHER; PTHR13317; PTHR13317; 1.
DR   Pfam; PF05346; DUF747; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..828
FT                   /note="Protein TAPT1 homolog"
FT                   /id="PRO_0000328881"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        472..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        722..742
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        754..774
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          67..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          797..828
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   828 AA;  93486 MW;  50453E0A1E2BBA56 CRC64;
     MEDKNILYES IPTSTNNNEL LPLQLIPIKP NITQEEQDLL DNIVKNESII PMSPKIPINI
     NNNNTINNNN NNNSNNVSSG NHITNSNSNS SGNLKDSFDL NSVIDSTCVM TSPIAVSPPI
     INKLINNKEN ILNINGILEN NINCTNDNQE LINILLNKNQ LQQQQQQQQQ LYLQQQQLQQ
     LQQQIQQIQQ QLQQQQQQNS IFRPITPKII DQQTQPQPQP QTQTTQQPSS QQPFSYEKTP
     VLASRTISTQ KSNSPIPFPN LGTLINDPIN STSSTASNTK SQIPSTPLLV KSTENIQTTP
     QSNNNDNNDN NNNNNSKNNN NLTDINEDKN NGIEQSSSGN TTTSSITMTA AATTTTTTTT
     ATTATTTTAT TTSIKVEPKK KSTSLWSFKT YLYDEIHGGY LSNEANDTLK REQVYNFVHV
     PWELEKLISF GFLVCFDSFL FLFTFLPIRF FLSFLKFLIS PFSKKNKLTT NQIFDLFRGF
     IWVTCFVFLN FIDSSMLYHY IRGQAVIKLY VIYNVLEVLD KLCCSFGQDI FDSLYWMSFS
     LTSSNRNRQD GLVPKQRNET RILGPFTHLL VATGYVCLHS LVLFSQVITL NVAINSYNNA
     LLTLMISNQF VELKGSVFKR FEKENLFQIS CSDIVERFQA FIFLTIIIFQ NLSDLNWDLS
     WDFAINMLTV VGTVWGSEVL VDAIKHAFIT KFNKFSPQMY SKFFVLLSDT IVDPRNRNFT
     ESSWGVNNII GFVPFPLASI VVRVFHKFIP SKGIFGIFLM VQIYICLVLL KIFIKIIILG
     QCLSKTTNYD NTTTTILSSS SSSSSSNSLN TTSTTSTSTS TTNDKKNN