ID   TATAO_HALVD             Reviewed;          90 AA.
AC   D4GVK4;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Sec-independent protein translocase protein TatAo {ECO:0000255|HAMAP-Rule:MF_00236};
GN   Name=tatAo {ECO:0000255|HAMAP-Rule:MF_00236}; OrderedLocusNames=HVO_1027;
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2;
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
RN   [2]
RP   FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RC   STRAIN=DS2 / DS70 / H99;
RX   PubMed=16291683; DOI=10.1128/jb.187.23.8104-8113.2005;
RA   Dilks K., Gimenez M.I., Pohlschroder M.;
RT   "Genetic and biochemical analysis of the twin-arginine translocation
RT   pathway in halophilic archaea.";
RL   J. Bacteriol. 187:8104-8113(2005).
CC   -!- FUNCTION: Part of the twin-arginine translocation (Tat) system that
CC       transports large folded proteins containing a characteristic twin-
CC       arginine motif in their signal peptide across membranes. TatA could
CC       form the protein-conducting channel of the Tat system (Probable).
CC       {ECO:0000305|PubMed:16291683}.
CC   -!- SUBUNIT: Forms a complex with TatC (By similarity). Cytoplasmic and
CC       membrane-bound TatA form high-molecular-weight complexes.
CC       {ECO:0000255|HAMAP-Rule:MF_00236, ECO:0000269|PubMed:16291683}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00236,
CC       ECO:0000269|PubMed:16291683}; Single-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_00236, ECO:0000269|PubMed:16291683}.
CC       Cytoplasm {ECO:0000269|PubMed:16291683}.
CC   -!- MISCELLANEOUS: H.volcanii possesses two TatA translocases: TatAo and
CC       TatAt. Each may interact with specific Tat substrates
CC       (PubMed:16291683). {ECO:0000305|PubMed:16291683}.
CC   -!- SIMILARITY: Belongs to the TatA/E family. {ECO:0000255|HAMAP-
CC       Rule:MF_00236}.
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DR   EMBL; CP001956; ADE04997.1; -; Genomic_DNA.
DR   RefSeq; WP_004043915.1; NZ_AOHU01000092.1.
DR   AlphaFoldDB; D4GVK4; -.
DR   SMR; D4GVK4; -.
DR   STRING; 309800.C498_13624; -.
DR   TCDB; 2.A.64.4.1; the twin arginine targeting (tat) family.
DR   EnsemblBacteria; ADE04997; ADE04997; HVO_1027.
DR   GeneID; 8924188; -.
DR   KEGG; hvo:HVO_1027; -.
DR   eggNOG; arCOG02694; Archaea.
DR   HOGENOM; CLU_086034_3_3_2; -.
DR   OMA; IMGDIPG; -.
DR   Proteomes; UP000008243; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0033281; C:TAT protein transport complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043953; P:protein transport by the Tat complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00236; TatA_E; 1.
DR   InterPro; IPR003369; TatA/B/E.
DR   InterPro; IPR006312; TatA/E.
DR   Pfam; PF02416; TatA_B_E; 1.
DR   TIGRFAMs; TIGR01411; tatAE; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Cytoplasm; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..90
FT                   /note="Sec-independent protein translocase protein TatAo"
FT                   /id="PRO_0000417358"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00236"
FT   REGION          39..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..66
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..83
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   90 AA;  9583 MW;  6A2B39BAC0E8F6ED CRC64;
     MLDSIPLFPG LPGGPELLIV LLIVVLLFGA NKLPQLARSS GQAMGEFRRG REEIEEELKK
     GAEGGDDEGE NGDEAEADDA DATETEAESR