BPTA_BORAF
ID BPTA_BORAF Reviewed; 206 AA.
AC Q56NH1;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Protein BptA;
DE AltName: Full=Borrelial persistence in ticks protein A;
DE Flags: Precursor;
GN Name=bptA;
OS Borreliella afzelii (Borrelia afzelii).
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=29518;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BO23;
RX PubMed=15860579; DOI=10.1073/pnas.0502565102;
RA Revel A.T., Blevins J.S., Almazan C., Neil L., Kocan K.M., de la Fuente J.,
RA Hagman K.E., Norgard M.V.;
RT "bptA (bbe16) is essential for the persistence of the Lyme disease
RT spirochete, Borrelia burgdorferi, in its natural tick vector.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:6972-6977(2005).
CC -!- FUNCTION: Virulence-associated protein essential for survival of the
CC bacterium within the tick host and therefore within the natural life
CC cycle of the Lyme disease spirochete. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BptA family. {ECO:0000305}.
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DR EMBL; AY894347; AAX69074.1; -; Genomic_DNA.
DR AlphaFoldDB; Q56NH1; -.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR031471; BptA.
DR Pfam; PF17044; BPTA; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal; Virulence.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..206
FT /note="Protein BptA"
FT /id="PRO_0000240471"
SQ SEQUENCE 206 AA; 24617 MW; 112E736C8348052A CRC64;
MSRILFYGLL LICIFLGFFF YKQKENNIIY NRIVEKFEDN VVIDEIYTHL FKDSNLKELV
FIKSQLIIPE LEHKKMIKAT GYRADAYKAL STVYRFDFKV HDNKILGFKS VIFEGFEDAK
VSKHENNLPS EKWQQLKDFN IGDPNINEKF FHLEFPFVVK NTLCVTISKG FFKKIKKLKR
LKIMLISNED REYKIDIENF LPKYNL