ID   BPTA_BORBD              Reviewed;         206 AA.
AC   Q56NG9; G0AP19;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Protein BptA;
DE   AltName: Full=Borrelial persistence in ticks protein A;
DE   Flags: Precursor;
GN   Name=bptA; OrderedLocusNames=BbiDN127_E0008;
OS   Borrelia bissettiae (strain DSM 17990 / CIP 109136 / DN127) (Borreliella
OS   bissettiae).
OG   Plasmid lp25.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=521010;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 17990 / CIP 109136 / DN127;
RX   PubMed=15860579; DOI=10.1073/pnas.0502565102;
RA   Revel A.T., Blevins J.S., Almazan C., Neil L., Kocan K.M., de la Fuente J.,
RA   Hagman K.E., Norgard M.V.;
RT   "bptA (bbe16) is essential for the persistence of the Lyme disease
RT   spirochete, Borrelia burgdorferi, in its natural tick vector.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:6972-6977(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17990 / CIP 109136 / DN127; PLASMID=lp25;
RA   Mongodin E.F., Casjens S.R., Fraser-Liggett C.M., Qiu W.-G., Dunn J.J.,
RA   Luft B.J., Schutzer S.E.;
RT   "Complete genome sequence of Borrelia bissettii strain DN127.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Virulence-associated protein essential for survival of the
CC       bacterium within the tick host and therefore within the natural life
CC       cycle of the spirochete. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BptA family. {ECO:0000305}.
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DR   EMBL; AY894349; AAX69076.1; -; Genomic_DNA.
DR   EMBL; CP002757; AEL19445.1; -; Genomic_DNA.
DR   RefSeq; WP_014024058.1; NC_015922.1.
DR   AlphaFoldDB; Q56NG9; -.
DR   EnsemblBacteria; AEL19445; AEL19445; BbiDN127_E0008.
DR   KEGG; bbs:BbiDN127_E0008; -.
DR   HOGENOM; CLU_1329815_0_0_12; -.
DR   OrthoDB; 1214071at2; -.
DR   Proteomes; UP000001634; Plasmid lp25.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031471; BptA.
DR   Pfam; PF17044; BPTA; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Plasmid; Signal; Virulence.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..206
FT                   /note="Protein BptA"
FT                   /id="PRO_0000240472"
FT   CONFLICT        192
FT                   /note="E -> K (in Ref. 1; AAX69076)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   206 AA;  24712 MW;  65C0FB5504867E71 CRC64;
     MRKILFFGLL SICFLFVFFF YKQKENKIIY NKIVEKFEDN VVIDETYTHL FKDSNLKELV
     FIKSRLIIPE LEHKKMMKAT GYRADAYRAL STVYKFDFKV HDNKILGFKS VIFEGFEDAK
     VSKHENNLPS EKWQQLKDFN IGDPNINEKF FHLEFPFVVK NTLCVTISKG FFKKIKKLKR
     LKIMLISNED REYKIDIENF LPKYNL