TATA_MAIZE
ID TATA_MAIZE Reviewed; 170 AA.
AC Q9XFJ8; B6TQH7; C0PD76;
DT 31-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2017, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Sec-independent protein translocase protein TATA, chloroplastic {ECO:0000305};
DE AltName: Full=Protein THYLAKOID ASSEMBLY 4 {ECO:0000303|PubMed:10525534};
DE AltName: Full=Protein TWIN-ARGININE TRANSLOCATION A {ECO:0000305};
DE Flags: Precursor;
GN Name=TATA {ECO:0000305|PubMed:10525534};
GN Synonyms=THA4 {ECO:0000303|PubMed:10525534};
GN ORFNames=ZEAMMB73_Zm00001d033317 {ECO:0000312|EMBL:ONM07224.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TOPOLOGY,
RP TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. B73 Inbred;
RX PubMed=10525534; DOI=10.1083/jcb.147.2.267;
RA Walker M.B., Roy L.M., Coleman E., Voelker R., Barkan A.;
RT "The maize tha4 gene functions in sec-independent protein transport in
RT chloroplasts and is related to hcf106, tatA, and tatB.";
RL J. Cell Biol. 147:267-276(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73;
RX PubMed=19965430; DOI=10.1126/science.1178534;
RA Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT "The B73 maize genome: complexity, diversity, and dynamics.";
RL Science 326:1112-1115(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. B73;
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [5]
RP DISRUPTION PHENOTYPE.
RX PubMed=7664731; DOI=10.1002/j.1460-2075.1995.tb00062.x;
RA Voelker R., Barkan A.;
RT "Two nuclear mutations disrupt distinct pathways for targeting proteins to
RT the chloroplast thylakoid.";
RL EMBO J. 14:3905-3914(1995).
CC -!- FUNCTION: Part of the twin-arginine translocation (Tat) system that
CC transports large folded proteins containing a characteristic twin-
CC arginine motif in their signal peptide across the thylakoid membrane.
CC Involved in delta pH-dependent protein transport required for
CC chloroplast development, especially thylakoid membrane formation. TATC
CC and TATB mediate precursor recognition, whereas TATA facilitates
CC translocation. {ECO:0000269|PubMed:10525534}.
CC -!- SUBUNIT: In thylakoid membranes, TATC and TATB form a large receptor
CC complex, containing about eight TATC-TATB pairs, which binds the
CC precursor protein. Twin arginine signal peptide promotes pH-triggered
CC docking of TATA oligomers to TATC-TATB receptor complex, inducing a
CC conformational switch of TATA that results in activation of the
CC translocase. TATA dissociates from TATC-TATB upon completion of
CC translocation (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000305|PubMed:10525534}; Single-pass membrane protein
CC {ECO:0000305|PubMed:10525534}. Note=The C-terminus is located in the
CC stroma.
CC -!- DISRUPTION PHENOTYPE: Seedling lethality after the development of three
CC to four leaves. Non-photosynthetic mutants possess near normal pigment
CC levels but lack one or more elements of the electron transport activity
CC in chloroplasts. Defects in protein targeting across chloroplast
CC thylakoid membrane (PubMed:7664731). {ECO:0000269|PubMed:10525534,
CC ECO:0000269|PubMed:7664731}.
CC -!- SIMILARITY: Belongs to the TatA/E family. {ECO:0000305}.
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DR EMBL; AF145755; AAD31522.1; -; mRNA.
DR EMBL; CM007647; ONM07224.1; -; Genomic_DNA.
DR EMBL; EU967242; ACG39360.1; -; mRNA.
DR EMBL; BT066245; ACN32121.1; -; mRNA.
DR RefSeq; NP_001150512.2; NM_001157040.2.
DR AlphaFoldDB; Q9XFJ8; -.
DR STRING; 4577.GRMZM2G472651_P01; -.
DR PaxDb; Q9XFJ8; -.
DR PRIDE; Q9XFJ8; -.
DR EnsemblPlants; Zm00001eb051040_T002; Zm00001eb051040_P002; Zm00001eb051040.
DR GeneID; 541788; -.
DR Gramene; Zm00001eb051040_T002; Zm00001eb051040_P002; Zm00001eb051040.
DR KEGG; zma:541788; -.
DR MaizeGDB; 1233219; -.
DR eggNOG; ENOG502S4T0; Eukaryota.
DR OMA; PPNEMAV; -.
DR OrthoDB; 1641169at2759; -.
DR Proteomes; UP000007305; Chromosome 1.
DR ExpressionAtlas; Q9XFJ8; baseline and differential.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IDA:UniProtKB.
DR GO; GO:0031361; C:integral component of thylakoid membrane; IDA:UniProtKB.
DR GO; GO:0009977; F:proton motive force dependent protein transmembrane transporter activity; IMP:UniProtKB.
DR GO; GO:0045038; P:protein import into chloroplast thylakoid membrane; IMP:UniProtKB.
DR GO; GO:0043953; P:protein transport by the Tat complex; IMP:UniProtKB.
DR HAMAP; MF_00236; TatA_E; 1.
DR InterPro; IPR003369; TatA/B/E.
DR InterPro; IPR006312; TatA/E.
DR Pfam; PF02416; TatA_B_E; 1.
DR TIGRFAMs; TIGR01411; tatAE; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Membrane; Plastid; Protein transport; Reference proteome;
KW Thylakoid; Transit peptide; Translocation; Transmembrane;
KW Transmembrane helix; Transport.
FT TRANSIT 1..61
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 62..170
FT /note="Sec-independent protein translocase protein TATA,
FT chloroplastic"
FT /id="PRO_0000419920"
FT TOPO_DOM 62..84
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..170
FT /note="Stromal"
FT /evidence="ECO:0000255"
FT REGION 130..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 26
FT /note="A -> G (in Ref. 1; AAD31522)"
FT CONFLICT 59
FT /note="A -> S (in Ref. 3; ACG39360)"
FT /evidence="ECO:0000305"
FT CONFLICT 158
FT /note="E -> D (in Ref. 3; ACG39360)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 170 AA; 16440 MW; ECD86A98481EEE59 CRC64;
MGIPVVVPVA AAYSCSSSLA APPRAAAAAA RAPSRAHVAA AGMSSRASSF VGGSGGDLAA
VAASVAARPR RAGSGGGGAL GCKCLFGLGV PELAVIAGVA ALVFGPKQLP EIGRSIGKTV
KSFQQAAKEF ETELKKEPGE GGDQPPPATP TAVSGGEEKG LEASSSKESA
