AC124_NPVAC
ID AC124_NPVAC Reviewed; 247 AA.
AC P41679;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 29-SEP-2021, entry version 38.
DE RecName: Full=Protein AC124;
OS Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX NCBI_TaxID=46015;
OH NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=L1;
RX PubMed=8178427; DOI=10.1006/viro.1994.1200;
RA Morris T.D., Todd J.W., Fisher B., Miller L.K.;
RT "Identification of lef-7: a baculovirus gene affecting late gene
RT expression.";
RL Virology 200:360-369(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C6;
RX PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT virus.";
RL Virology 202:586-605(1994).
RN [3]
RP FUNCTION.
RX PubMed=25380680; DOI=10.1007/s00705-014-2277-y;
RA Liang C., Lan D., Zhao S., Liu L., Xue Y., Zhang Y., Wang Y., Chen X.;
RT "The Ac124 protein is not essential for the propagation of Autographa
RT californica multiple nucleopolyhedrovirus, but it is a viral pathogenicity
RT factor.";
RL Arch. Virol. 160:275-284(2015).
CC -!- FUNCTION: Accelerates mortality in insect larvae.
CC {ECO:0000269|PubMed:25380680}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:25380680}.
CC Host nucleus {ECO:0000269|PubMed:25380680}. Note=Present in the host
CC cytoplasm from 24 hours to 48 hours post infection. At 48 hours,
CC localizes throughout the cytoplasm and the nucleus.
CC {ECO:0000269|PubMed:25380680}.
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DR EMBL; U01142; -; NOT_ANNOTATED_CDS; Unassigned_DNA.
DR EMBL; L22858; AAA66754.1; -; Genomic_DNA.
DR PIR; E72865; E72865.
DR RefSeq; NP_054154.1; NC_001623.1.
DR GeneID; 1403957; -.
DR KEGG; vg:1403957; -.
DR Proteomes; UP000008292; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE 4: Predicted;
KW Host cytoplasm; Host nucleus; Reference proteome.
FT CHAIN 1..247
FT /note="Protein AC124"
FT /id="PRO_0000133062"
SQ SEQUENCE 247 AA; 28530 MW; EAC5FB45C1FEBFE1 CRC64;
MGLFACCTKY TRLSTDTKMK FPYVALSYIN VTLCTYTAML VGYMVTFNDS SELKYLQYWL
LLSFLMSVVL NAPTLWTMLK TTEAHEVIYE MKLFHAMYFS NVLLNYVVFL DNQMGTNFVF
VNNLIHCCVL FMIFVELLIL LGHTMGTYTD YQYVKSCYMV ILFVSVMSVT IVMGLECLKT
KLIDNSLMFN AFVCALYIVI AIMWSLKNNL TSYYVSNLQS IQVVPFSYND PPPPFSNIVM
DDIKNKK