ID   TATC_AKKM8              Reviewed;         348 AA.
AC   B2UN92;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Sec-independent protein translocase protein TatC {ECO:0000255|HAMAP-Rule:MF_00902};
GN   Name=tatC {ECO:0000255|HAMAP-Rule:MF_00902}; OrderedLocusNames=Amuc_1889;
OS   Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS   81048 / CCUG 64013 / CIP 107961 / Muc).
OC   Bacteria; Verrucomicrobia; Verrucomicrobiae; Verrucomicrobiales;
OC   Akkermansiaceae; Akkermansia.
OX   NCBI_TaxID=349741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP
RC   107961 / Muc;
RX   PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA   van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA   Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT   "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT   degrader, and its use in exploring intestinal metagenomes.";
RL   PLoS ONE 6:E16876-E16876(2011).
CC   -!- FUNCTION: Part of the twin-arginine translocation (Tat) system that
CC       transports large folded proteins containing a characteristic twin-
CC       arginine motif in their signal peptide across membranes.
CC       {ECO:0000255|HAMAP-Rule:MF_00902}.
CC   -!- SUBUNIT: Forms a complex with TatA. {ECO:0000255|HAMAP-Rule:MF_00902}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00902};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00902}.
CC   -!- SIMILARITY: Belongs to the TatC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00902}.
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DR   EMBL; CP001071; ACD05703.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2UN92; -.
DR   SMR; B2UN92; -.
DR   STRING; 349741.Amuc_1889; -.
DR   EnsemblBacteria; ACD05703; ACD05703; Amuc_1889.
DR   KEGG; amu:Amuc_1889; -.
DR   eggNOG; COG0805; Bacteria.
DR   HOGENOM; CLU_796048_0_0_0; -.
DR   Proteomes; UP000001031; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0033281; C:TAT protein transport complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043953; P:protein transport by the Tat complex; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00902; TatC; 1.
DR   InterPro; IPR002033; TatC.
DR   PANTHER; PTHR30371; PTHR30371; 1.
DR   Pfam; PF00902; TatC; 1.
DR   PRINTS; PR01840; TATCFAMILY.
DR   TIGRFAMs; TIGR00945; tatC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Reference proteome;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..348
FT                   /note="Sec-independent protein translocase protein TatC"
FT                   /id="PRO_0000412858"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
SQ   SEQUENCE   348 AA;  38944 MW;  6CBD2FD5DDD328AC CRC64;
     MLLRMALCLT VSTILCAGFA SNLMDILRRP VNQVWDMFEE SHLPAGIGLD AWSKAKEMAT
     AMTSLGASQR ALFLRQVSPS QADLTEAALV LRGAQPLPED RKQVFIREGS PSTAVRDLAE
     ALYSKGAVLA DGTGRGALKM MSAFQPGEAF MLTIKLSLYA GVVISFPLLL YFLLQFIIPG
     LLEHERKLLY KCMAVGFGLF LAGTLFCYFI VLPRVLTFFY TYSLEFGISN EWRIGYYLSF
     ATQMILMFGL AFELPVVVMP FVKLGVLTYD MMKSTRRYAI VAIAVLAAVI TPTPDVATMM
     LMAVPMYALY EICIILAWMH ERKEAARTRE EIARFEEDFN NNNSPYNQ