ID   TATC_AQUAE              Reviewed;         240 AA.
AC   O67305;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Sec-independent protein translocase protein TatC {ECO:0000255|HAMAP-Rule:MF_00902};
GN   Name=tatC {ECO:0000255|HAMAP-Rule:MF_00902}; OrderedLocusNames=aq_1267;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Part of the twin-arginine translocation (Tat) system that
CC       transports large folded proteins containing a characteristic twin-
CC       arginine motif in their signal peptide across membranes.
CC       {ECO:0000255|HAMAP-Rule:MF_00902}.
CC   -!- SUBUNIT: Forms a complex with TatA. {ECO:0000255|HAMAP-Rule:MF_00902}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00902}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00902}.
CC   -!- SIMILARITY: Belongs to the TatC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00902}.
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DR   EMBL; AE000657; AAC07267.1; -; Genomic_DNA.
DR   PIR; F70409; F70409.
DR   RefSeq; NP_213869.1; NC_000918.1.
DR   RefSeq; WP_010880807.1; NC_000918.1.
DR   PDB; 4B4A; X-ray; 3.50 A; A=1-240.
DR   PDB; 4HTS; X-ray; 4.00 A; A=1-232.
DR   PDB; 4HTT; X-ray; 6.80 A; A/B=1-235.
DR   PDBsum; 4B4A; -.
DR   PDBsum; 4HTS; -.
DR   PDBsum; 4HTT; -.
DR   AlphaFoldDB; O67305; -.
DR   SMR; O67305; -.
DR   STRING; 224324.aq_1267; -.
DR   EnsemblBacteria; AAC07267; AAC07267; aq_1267.
DR   KEGG; aae:aq_1267; -.
DR   PATRIC; fig|224324.8.peg.988; -.
DR   eggNOG; COG0805; Bacteria.
DR   HOGENOM; CLU_031942_3_3_0; -.
DR   InParanoid; O67305; -.
DR   OMA; HFWKSIF; -.
DR   OrthoDB; 1848013at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0033281; C:TAT protein transport complex; IBA:GO_Central.
DR   GO; GO:0009977; F:proton motive force dependent protein transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IBA:GO_Central.
DR   GO; GO:0043953; P:protein transport by the Tat complex; IBA:GO_Central.
DR   HAMAP; MF_00902; TatC; 1.
DR   InterPro; IPR019820; Sec-indep_translocase_CS.
DR   InterPro; IPR002033; TatC.
DR   PANTHER; PTHR30371; PTHR30371; 1.
DR   Pfam; PF00902; TatC; 1.
DR   PRINTS; PR01840; TATCFAMILY.
DR   TIGRFAMs; TIGR00945; tatC; 1.
DR   PROSITE; PS01218; TATC; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell inner membrane; Cell membrane; Membrane;
KW   Protein transport; Reference proteome; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..240
FT                   /note="Sec-independent protein translocase protein TatC"
FT                   /id="PRO_0000098093"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00902"
FT   HELIX           6..30
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           32..46
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   STRAND          56..58
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           60..88
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   TURN            89..92
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   TURN            97..100
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           101..120
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           122..128
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   TURN            129..131
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   STRAND          133..135
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   STRAND          138..141
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           146..163
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           166..175
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           181..202
FT                   /evidence="ECO:0007829|PDB:4B4A"
FT   HELIX           206..225
FT                   /evidence="ECO:0007829|PDB:4B4A"
SQ   SEQUENCE   240 AA;  27129 MW;  FC3125C54D5B9047 CRC64;
     MPLTEHLREL RYRLIISIIA FLIGSGIAFY FAKYVFEILK EPILKSYPEV ELITLSPTEP
     LFILIKISLA VGFIIASPVI LYQFWRFIEP ALYSHEKRAF IPLLLGSILL FMLGALFAYF
     IVLPLALKFL LGLGFTQLLA TPYLSVDMYI SFVLKLVVAF GIAFEMPIVL YVLQKAGVIT
     PEQLASFRKY FIVIAFVIGA IIAPDVSTQV LMAIPLLLLY EISIFLGKLA TRKKKEIQKA