TATE_ECOLI
ID TATE_ECOLI Reviewed; 67 AA.
AC P0A843; P25895; P77420;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Sec-independent protein translocase protein TatE;
GN Name=tatE {ECO:0000255|HAMAP-Rule:MF_00903}; Synonyms=ybeC;
GN OrderedLocusNames=b0627, JW0622;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1577793; DOI=10.1016/s0021-9258(19)50120-x;
RA Hayden M.A., Huang I., Bussiere D.E., Ashley G.W.;
RT "The biosynthesis of lipoic acid. Cloning of lip, a lipoate biosynthetic
RT locus of Escherichia coli.";
RL J. Biol. Chem. 267:9512-9515(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [6]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX PubMed=9649434; DOI=10.1093/emboj/17.13.3640;
RA Sargent F., Bogsch E.G., Stanley N.R., Wexler M., Robinson C., Berks B.C.,
RA Palmer T.;
RT "Overlapping functions of components of a bacterial Sec-independent protein
RT export pathway.";
RL EMBO J. 17:3640-3650(1998).
RN [7]
RP REVIEW.
RX PubMed=10652088; DOI=10.1046/j.1365-2958.2000.01719.x;
RA Berks B.C., Sargent F., Palmer T.;
RT "The Tat protein export pathway.";
RL Mol. Microbiol. 35:260-274(2000).
RN [8]
RP INDUCTION.
RX PubMed=11160116; DOI=10.1128/jb.183.5.1801-1804.2001;
RA Jack R.L., Sargent F., Berks B.C., Sawers G., Palmer T.;
RT "Constitutive expression of Escherichia coli tat genes indicates an
RT important role for the twin-arginine translocase during aerobic and
RT anaerobic growth.";
RL J. Bacteriol. 183:1801-1804(2001).
CC -!- FUNCTION: Part of the twin-arginine translocation (Tat) system that
CC transports large folded proteins containing a characteristic twin-
CC arginine motif in their signal peptide across membranes. TatE shares
CC overlapping functions with TatA. {ECO:0000255|HAMAP-Rule:MF_00903,
CC ECO:0000269|PubMed:9649434}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00903}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00903}.
CC -!- INDUCTION: Constitutively expressed. {ECO:0000269|PubMed:11160116}.
CC -!- DISRUPTION PHENOTYPE: Disruption of tatE affects the correct
CC localization of multiple enzymes whose precursors bear twin arginine
CC transfer peptides. Export is completely blocked when both tatA and tatE
CC are inactivated. {ECO:0000269|PubMed:9649434}.
CC -!- SIMILARITY: Belongs to the TatA/E family. TatE subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_00903}.
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DR EMBL; M82805; AAA24073.1; -; Genomic_DNA.
DR EMBL; U82598; AAB40827.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73728.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35270.1; -; Genomic_DNA.
DR PIR; JN0256; JN0256.
DR RefSeq; NP_415160.1; NC_000913.3.
DR RefSeq; WP_000503931.1; NZ_STEB01000031.1.
DR AlphaFoldDB; P0A843; -.
DR SMR; P0A843; -.
DR BioGRID; 4260637; 293.
DR ComplexPortal; CPX-3445; Twin-arginine translocation complex.
DR IntAct; P0A843; 56.
DR STRING; 511145.b0627; -.
DR TCDB; 2.A.64.1.1; the twin arginine targeting (tat) family.
DR PaxDb; P0A843; -.
DR PRIDE; P0A843; -.
DR EnsemblBacteria; AAC73728; AAC73728; b0627.
DR EnsemblBacteria; BAA35270; BAA35270; BAA35270.
DR GeneID; 67416330; -.
DR GeneID; 945228; -.
DR KEGG; ecj:JW0622; -.
DR KEGG; eco:b0627; -.
DR PATRIC; fig|1411691.4.peg.1641; -.
DR EchoBASE; EB1282; -.
DR eggNOG; COG1826; Bacteria.
DR HOGENOM; CLU_086034_5_3_6; -.
DR InParanoid; P0A843; -.
DR OMA; KDGMREG; -.
DR PhylomeDB; P0A843; -.
DR BioCyc; EcoCyc:EG11305-MON; -.
DR BioCyc; MetaCyc:EG11305-MON; -.
DR PRO; PR:P0A843; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0033281; C:TAT protein transport complex; IMP:EcoCyc.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IGI:EcoliWiki.
DR GO; GO:0043953; P:protein transport by the Tat complex; IC:ComplexPortal.
DR HAMAP; MF_00236; TatA_E; 1.
DR HAMAP; MF_00903; TatE; 1.
DR InterPro; IPR003369; TatA/B/E.
DR InterPro; IPR006312; TatA/E.
DR InterPro; IPR024905; TatE.
DR Pfam; PF02416; TatA_B_E; 1.
DR TIGRFAMs; TIGR01411; tatAE; 1.
PE 2: Evidence at transcript level;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..67
FT /note="Sec-independent protein translocase protein TatE"
FT /id="PRO_0000097973"
FT TRANSMEM 4..21
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00903"
FT CONFLICT 44
FT /note="N -> I (in Ref. 1; AAA24073)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 67 AA; 7024 MW; FA880C6DECE248A3 CRC64;
MGEISITKLL VVAALVVLLF GTKKLRTLGG DLGAAIKGFK KAMNDDDAAA KKGADVDLQA
EKLSHKE
