ID   TAUE_CUPNH              Reviewed;         256 AA.
AC   Q0K020;
DT   22-NOV-2017, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Probable sulfite/organosulfonate exporter TauE {ECO:0000303|PubMed:22797525};
GN   Name=tauE {ECO:0000303|PubMed:17768248};
GN   OrderedLocusNames=H16_B1872 {ECO:0000312|EMBL:CAJ96654.1};
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Poetter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
RN   [2]
RP   FUNCTION, AND INDUCTION.
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=17768248; DOI=10.1099/mic.0.2007/009845-0;
RA   Weinitschke S., Denger K., Cook A.M., Smits T.H.;
RT   "The DUF81 protein TauE in Cupriavidus necator H16, a sulfite exporter in
RT   the metabolism of C2 sulfonates.";
RL   Microbiology 153:3055-3060(2007).
RN   [3]
RP   FUNCTION.
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337;
RX   PubMed=22797525; DOI=10.1007/s00203-012-0825-y;
RA   Mayer J., Denger K., Hollemeyer K., Schleheck D., Cook A.M.;
RT   "(R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with
RT   excretion of 3-sulfolactate: a patchwork pathway.";
RL   Arch. Microbiol. 194:949-957(2012).
CC   -!- FUNCTION: Could be a sulfite/organosulfonate exporter with a wide
CC       substrate range, including 3-sulfolactate and 3-sulfopyruvate.
CC       {ECO:0000269|PubMed:17768248, ECO:0000269|PubMed:22797525}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- INDUCTION: Induced by the C2 sulfonates taurine, isethionate and
CC       sulfoacetate. {ECO:0000269|PubMed:17768248}.
CC   -!- SIMILARITY: Belongs to the 4-toluene sulfonate uptake permease (TSUP)
CC       (TC 2.A.102) family. {ECO:0000305}.
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DR   EMBL; AM260480; CAJ96654.1; -; Genomic_DNA.
DR   RefSeq; WP_011617520.1; NZ_CP039288.1.
DR   AlphaFoldDB; Q0K020; -.
DR   STRING; 381666.H16_B1872; -.
DR   TCDB; 2.A.102.2.1; the 4-toluene sulfonate uptake permease (tsup) family.
DR   EnsemblBacteria; CAJ96654; CAJ96654; H16_B1872.
DR   GeneID; 57647775; -.
DR   KEGG; reh:H16_B1872; -.
DR   eggNOG; COG0730; Bacteria.
DR   HOGENOM; CLU_054750_3_0_4; -.
DR   OMA; HIDWRAV; -.
DR   OrthoDB; 1274094at2; -.
DR   Proteomes; UP000008210; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002781; TM_pro_TauE-like.
DR   Pfam; PF01925; TauE; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..256
FT                   /note="Probable sulfite/organosulfonate exporter TauE"
FT                   /id="PRO_0000442432"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   256 AA;  26242 MW;  AA2920FFFE24C71D CRC64;
     MKAELLLPLL GLQALLGAGT YFQTVTGFGL GMIVMGVTSG LGLAPVATVA AVVSLVTLAN
     SACALPGKLQ HIDWRAVAAA AIGILPSVVV GVLVLEYLSS SAATLLQLLL GAVILYGGLS
     AALKPAPLAQ RSGDGTFFVS GVFGGLLSGM FGVSGPPLIF QFYRQPMKPV EIRCALILVF
     TVTSTVRTLF SAWQGQLDAA VCVQAAIAVP VVVIATLLGR RFPPPFSPAT TRRVAFGVLI
     GIGASLMLPA ISAWVL