TAX1_ARATH
ID TAX1_ARATH Reviewed; 75 AA.
AC O82275;
DT 16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Signaling peptide TAXIMIN 1 {ECO:0000303|PubMed:26071531};
DE Flags: Precursor;
GN Name=TAX1 {ECO:0000303|PubMed:26071531};
GN OrderedLocusNames=At2g31090 {ECO:0000312|Araport:AT2G31090};
GN ORFNames=T16B12.10 {ECO:0000312|EMBL:AAC63841.2};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Columbia;
RX PubMed=26071531; DOI=10.1093/jxb/erv291;
RA Colling J., Tohge T., De Clercq R., Brunoud G., Vernoux T., Fernie A.R.,
RA Makunga N.P., Goossens A., Pauwels L.;
RT "Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1
RT affects lateral organ development.";
RL J. Exp. Bot. 66:5337-5349(2015).
RN [7]
RP FUNCTION, ACTIVITY REGULATION, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=26967827; DOI=10.1080/15592324.2016.1143998;
RA Colling J., Pollier J., Vanden Bossche R., Makunga N.P., Pauwels L.,
RA Goossens A.;
RT "Hypersensitivity of Arabidopsis TAXIMIN1 overexpression lines to light
RT stress is correlated with decreased sinapoyl malate abundance and countered
RT by the antibiotic cefotaxime.";
RL Plant Signal. Behav. 11:E1143998-E1143998(2016).
CC -!- FUNCTION: Signaling peptide involved in the regulation of lateral
CC organs separation, including fruits and leaves (PubMed:26071531).
CC Involved in the perception of and response to light stress via the
CC control of sinapoyl-malate accumulation, a UV-B protecting compound
CC (PubMed:26967827). {ECO:0000269|PubMed:26071531,
CC ECO:0000269|PubMed:26967827}.
CC -!- ACTIVITY REGULATION: Counteracted by the antibiotic cefotaxime during
CC responses to light stress. {ECO:0000269|PubMed:26967827}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26071531}.
CC -!- TISSUE SPECIFICITY: Expressed in shoot apical meristems (SAM); mostly
CC specific to the L1 layer in the center of the meristem but also
CC detected in the L2 layer in organ primordia. Also observed in the
CC vasculature of seedling roots. {ECO:0000269|PubMed:26071531}.
CC -!- DEVELOPMENTAL STAGE: Observed in seedlings shoot apical meristem (SAM).
CC Later present in the entire inflorescence meristem, and accumulates
CC strongly in organ primordia. In flowers, expressed in the anthers and
CC in the nectaries. Present in the paraclade junctions between the
CC primary stem and axillary stems, especially at the base of the cauline
CC leaf and the emerging axillary shoot. {ECO:0000269|PubMed:26071531}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:26071531, ECO:0000269|PubMed:26967827}.
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DR EMBL; AC005311; AAC63841.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC08492.1; -; Genomic_DNA.
DR EMBL; AK175340; BAD43103.1; -; mRNA.
DR EMBL; BT025565; ABF58983.1; -; mRNA.
DR EMBL; AY084503; AAM61072.1; -; mRNA.
DR PIR; D84716; D84716.
DR RefSeq; NP_565714.1; NM_128665.2.
DR AlphaFoldDB; O82275; -.
DR SMR; O82275; -.
DR IntAct; O82275; 3.
DR STRING; 3702.AT2G31090.1; -.
DR PaxDb; O82275; -.
DR PRIDE; O82275; -.
DR EnsemblPlants; AT2G31090.1; AT2G31090.1; AT2G31090.
DR GeneID; 817665; -.
DR Gramene; AT2G31090.1; AT2G31090.1; AT2G31090.
DR KEGG; ath:AT2G31090; -.
DR Araport; AT2G31090; -.
DR TAIR; locus:2055892; AT2G31090.
DR eggNOG; ENOG502S4K3; Eukaryota.
DR HOGENOM; CLU_180321_0_0_1; -.
DR InParanoid; O82275; -.
DR OMA; CDGDCRP; -.
DR PRO; PR:O82275; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82275; baseline and differential.
DR GO; GO:0005615; C:extracellular space; IDA:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0048530; P:fruit morphogenesis; IMP:TAIR.
DR GO; GO:0010199; P:organ boundary specification between lateral organs and the meristem; IMP:TAIR.
DR GO; GO:0009416; P:response to light stimulus; IMP:UniProtKB.
PE 2: Evidence at transcript level;
KW Developmental protein; Reference proteome; Secreted; Signal;
KW Stress response.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..75
FT /note="Signaling peptide TAXIMIN 1"
FT /id="PRO_0000446131"
SQ SEQUENCE 75 AA; 8150 MW; EF0E2DF683AB064E CRC64;
MCDGDCRPLG FLLGLPFAFL SLLLSIIGVI IWIVGLLLSC ICPCCLCVTV LVEIAIGLIK
APIHVMEWFM SKIPC
