TAX2_ARATH
ID TAX2_ARATH Reviewed; 73 AA.
AC Q1G309; A0MDZ4;
DT 16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Signaling peptide TAXIMIN 2 {ECO:0000303|PubMed:26071531};
DE Flags: Precursor;
GN Name=TAX2 {ECO:0000303|PubMed:26071531};
GN OrderedLocusNames=At2g20562 {ECO:0000312|Araport:AT2G20562};
GN ORFNames=T13C7 {ECO:0000312|EMBL:AC007109};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Columbia;
RX PubMed=26071531; DOI=10.1093/jxb/erv291;
RA Colling J., Tohge T., De Clercq R., Brunoud G., Vernoux T., Fernie A.R.,
RA Makunga N.P., Goossens A., Pauwels L.;
RT "Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1
RT affects lateral organ development.";
RL J. Exp. Bot. 66:5337-5349(2015).
RN [5]
RP DISRUPTION PHENOTYPE.
RX PubMed=26967827; DOI=10.1080/15592324.2016.1143998;
RA Colling J., Pollier J., Vanden Bossche R., Makunga N.P., Pauwels L.,
RA Goossens A.;
RT "Hypersensitivity of Arabidopsis TAXIMIN1 overexpression lines to light
RT stress is correlated with decreased sinapoyl malate abundance and countered
RT by the antibiotic cefotaxime.";
RL Plant Signal. Behav. 11:E1143998-E1143998(2016).
CC -!- FUNCTION: Signaling peptide involved in the regulation of lateral
CC organs separation. {ECO:0000250|UniProtKB:O82275}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:O82275}.
CC -!- TISSUE SPECIFICITY: Confined to the vasculature of various organs,
CC including seedling roots, leaves, cotyledons, sepals and petals.
CC Accumulates also in root hair cells. {ECO:0000269|PubMed:26071531}.
CC -!- DEVELOPMENTAL STAGE: In seedlings, observed at high levels in the
CC vasculature of cotyledons, first true leaves, and hypocoty. In flowers,
CC expressed in the vasculature of sepals, petals, and style. In the
CC paraclade junctions between the primary stem and axillary stems, mainly
CC detected in the vasculature of cauline leaves.
CC {ECO:0000269|PubMed:26071531}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:26071531, ECO:0000269|PubMed:26967827}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28360.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC007109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC07029.1; -; Genomic_DNA.
DR EMBL; DQ492219; ABF59148.1; -; mRNA.
DR EMBL; DQ652760; ABK28360.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001077925.1; NM_001084456.3.
DR AlphaFoldDB; Q1G309; -.
DR SMR; Q1G309; -.
DR STRING; 3702.AT2G20562.1; -.
DR PaxDb; Q1G309; -.
DR EnsemblPlants; AT2G20562.1; AT2G20562.1; AT2G20562.
DR GeneID; 5007888; -.
DR Gramene; AT2G20562.1; AT2G20562.1; AT2G20562.
DR KEGG; ath:AT2G20562; -.
DR Araport; AT2G20562; -.
DR TAIR; locus:4010713635; AT2G20562.
DR eggNOG; ENOG502S5CY; Eukaryota.
DR HOGENOM; CLU_180321_0_0_1; -.
DR InParanoid; Q1G309; -.
DR OMA; CICLPAL; -.
DR PhylomeDB; Q1G309; -.
DR PRO; PR:Q1G309; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q1G309; baseline and differential.
DR GO; GO:0005615; C:extracellular space; ISS:UniProtKB.
PE 2: Evidence at transcript level;
KW Developmental protein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..73
FT /note="Signaling peptide TAXIMIN 2"
FT /id="PRO_0000446132"
SQ SEQUENCE 73 AA; 7850 MW; 0B73B76F98D2A8FA CRC64;
MGDCRPLGFL IGLPFALVAL VLALVGAVIW IIGTVLSCLC PCCFCFAALA NFAVDLIKLP
IKVLRWFTHS IPC
