TBB5_WHEAT
ID TBB5_WHEAT Reviewed; 447 AA.
AC Q9ZRA8;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Tubulin beta-5 chain;
DE AltName: Full=Beta-5-tubulin;
GN Name=TUBB5;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Chinese Spring; TISSUE=Endosperm;
RA Segal G., Feldman M.;
RT "Tubb5, a beta-tubulin cDNA from common wheat.";
RL Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Tubulin is the major constituent of microtubules. It binds
CC two moles of GTP, one at an exchangeable site on the beta chain and one
CC at a non-exchangeable site on the alpha chain.
CC -!- SUBUNIT: Dimer of alpha and beta chains. A typical microtubule is a
CC hollow water-filled tube with an outer diameter of 25 nm and an inner
CC diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to
CC form protofilaments running lengthwise along the microtubule wall with
CC the beta-tubulin subunit facing the microtubule plus end conferring a
CC structural polarity. Microtubules usually have 13 protofilaments but
CC different protofilament numbers can be found in some organisms and
CC specialized cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the tubulin family. {ECO:0000305}.
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DR EMBL; U76896; AAD10492.1; -; mRNA.
DR AlphaFoldDB; Q9ZRA8; -.
DR SMR; Q9ZRA8; -.
DR STRING; 4565.Traes_1AL_E8C262A2A.2; -.
DR PRIDE; Q9ZRA8; -.
DR EnsemblPlants; TraesCAD_scaffold_009571_01G000400.1; TraesCAD_scaffold_009571_01G000400.1; TraesCAD_scaffold_009571_01G000400.
DR EnsemblPlants; TraesCAD_scaffold_020194_01G000200.1; TraesCAD_scaffold_020194_01G000200.1; TraesCAD_scaffold_020194_01G000200.
DR EnsemblPlants; TraesCAD_scaffold_105298_01G000200.1; TraesCAD_scaffold_105298_01G000200.1; TraesCAD_scaffold_105298_01G000200.
DR EnsemblPlants; TraesCLE_scaffold_017575_01G000200.1; TraesCLE_scaffold_017575_01G000200.1; TraesCLE_scaffold_017575_01G000200.
DR EnsemblPlants; TraesCLE_scaffold_103357_01G000100.1; TraesCLE_scaffold_103357_01G000100.1; TraesCLE_scaffold_103357_01G000100.
DR EnsemblPlants; TraesCLE_scaffold_127074_01G000200.1; TraesCLE_scaffold_127074_01G000200.1; TraesCLE_scaffold_127074_01G000200.
DR EnsemblPlants; TraesCS1A02G309700.1; TraesCS1A02G309700.1; TraesCS1A02G309700.
DR EnsemblPlants; TraesCS1B02G320800.1; TraesCS1B02G320800.1; TraesCS1B02G320800.
DR EnsemblPlants; TraesCS1D02G309200.1; TraesCS1D02G309200.1; TraesCS1D02G309200.
DR EnsemblPlants; TraesPAR_scaffold_011278_01G000200.1; TraesPAR_scaffold_011278_01G000200.1; TraesPAR_scaffold_011278_01G000200.
DR EnsemblPlants; TraesPAR_scaffold_050156_01G000200.1; TraesPAR_scaffold_050156_01G000200.1; TraesPAR_scaffold_050156_01G000200.
DR EnsemblPlants; TraesPAR_scaffold_095675_01G000200.1; TraesPAR_scaffold_095675_01G000200.1; TraesPAR_scaffold_095675_01G000200.
DR EnsemblPlants; TraesROB_scaffold_023685_01G000400.1; TraesROB_scaffold_023685_01G000400.1; TraesROB_scaffold_023685_01G000400.
DR EnsemblPlants; TraesROB_scaffold_042006_01G000100.1; TraesROB_scaffold_042006_01G000100.1; TraesROB_scaffold_042006_01G000100.
DR EnsemblPlants; TraesROB_scaffold_100911_01G000100.1; TraesROB_scaffold_100911_01G000100.1; TraesROB_scaffold_100911_01G000100.
DR EnsemblPlants; TraesWEE_scaffold_007631_01G000200.1; TraesWEE_scaffold_007631_01G000200.1; TraesWEE_scaffold_007631_01G000200.
DR EnsemblPlants; TraesWEE_scaffold_098495_01G000200.1; TraesWEE_scaffold_098495_01G000200.1; TraesWEE_scaffold_098495_01G000200.
DR EnsemblPlants; TraesWEE_scaffold_119188_01G000100.1; TraesWEE_scaffold_119188_01G000100.1; TraesWEE_scaffold_119188_01G000100.
DR Gramene; TraesCAD_scaffold_009571_01G000400.1; TraesCAD_scaffold_009571_01G000400.1; TraesCAD_scaffold_009571_01G000400.
DR Gramene; TraesCAD_scaffold_020194_01G000200.1; TraesCAD_scaffold_020194_01G000200.1; TraesCAD_scaffold_020194_01G000200.
DR Gramene; TraesCAD_scaffold_105298_01G000200.1; TraesCAD_scaffold_105298_01G000200.1; TraesCAD_scaffold_105298_01G000200.
DR Gramene; TraesCLE_scaffold_017575_01G000200.1; TraesCLE_scaffold_017575_01G000200.1; TraesCLE_scaffold_017575_01G000200.
DR Gramene; TraesCLE_scaffold_103357_01G000100.1; TraesCLE_scaffold_103357_01G000100.1; TraesCLE_scaffold_103357_01G000100.
DR Gramene; TraesCLE_scaffold_127074_01G000200.1; TraesCLE_scaffold_127074_01G000200.1; TraesCLE_scaffold_127074_01G000200.
DR Gramene; TraesCS1A02G309700.1; TraesCS1A02G309700.1; TraesCS1A02G309700.
DR Gramene; TraesCS1B02G320800.1; TraesCS1B02G320800.1; TraesCS1B02G320800.
DR Gramene; TraesCS1D02G309200.1; TraesCS1D02G309200.1; TraesCS1D02G309200.
DR Gramene; TraesPAR_scaffold_011278_01G000200.1; TraesPAR_scaffold_011278_01G000200.1; TraesPAR_scaffold_011278_01G000200.
DR Gramene; TraesPAR_scaffold_050156_01G000200.1; TraesPAR_scaffold_050156_01G000200.1; TraesPAR_scaffold_050156_01G000200.
DR Gramene; TraesPAR_scaffold_095675_01G000200.1; TraesPAR_scaffold_095675_01G000200.1; TraesPAR_scaffold_095675_01G000200.
DR Gramene; TraesROB_scaffold_023685_01G000400.1; TraesROB_scaffold_023685_01G000400.1; TraesROB_scaffold_023685_01G000400.
DR Gramene; TraesROB_scaffold_042006_01G000100.1; TraesROB_scaffold_042006_01G000100.1; TraesROB_scaffold_042006_01G000100.
DR Gramene; TraesROB_scaffold_100911_01G000100.1; TraesROB_scaffold_100911_01G000100.1; TraesROB_scaffold_100911_01G000100.
DR Gramene; TraesWEE_scaffold_007631_01G000200.1; TraesWEE_scaffold_007631_01G000200.1; TraesWEE_scaffold_007631_01G000200.
DR Gramene; TraesWEE_scaffold_098495_01G000200.1; TraesWEE_scaffold_098495_01G000200.1; TraesWEE_scaffold_098495_01G000200.
DR Gramene; TraesWEE_scaffold_119188_01G000100.1; TraesWEE_scaffold_119188_01G000100.1; TraesWEE_scaffold_119188_01G000100.
DR eggNOG; KOG1375; Eukaryota.
DR HOGENOM; CLU_015718_1_1_1; -.
DR OMA; QRELLWH; -.
DR Proteomes; UP000019116; Unplaced.
DR Genevisible; Q9ZRA8; TA.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR Gene3D; 1.10.287.600; -; 1.
DR Gene3D; 3.30.1330.20; -; 1.
DR Gene3D; 3.40.50.1440; -; 1.
DR InterPro; IPR013838; Beta-tubulin_BS.
DR InterPro; IPR002453; Beta_tubulin.
DR InterPro; IPR008280; Tub_FtsZ_C.
DR InterPro; IPR000217; Tubulin.
DR InterPro; IPR037103; Tubulin/FtsZ-like_C.
DR InterPro; IPR018316; Tubulin/FtsZ_2-layer-sand-dom.
DR InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR InterPro; IPR023123; Tubulin_C.
DR InterPro; IPR017975; Tubulin_CS.
DR InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR PANTHER; PTHR11588; PTHR11588; 1.
DR Pfam; PF00091; Tubulin; 1.
DR Pfam; PF03953; Tubulin_C; 1.
DR PRINTS; PR01163; BETATUBULIN.
DR PRINTS; PR01161; TUBULIN.
DR SMART; SM00864; Tubulin; 1.
DR SMART; SM00865; Tubulin_C; 1.
DR SUPFAM; SSF52490; SSF52490; 1.
DR SUPFAM; SSF55307; SSF55307; 1.
DR PROSITE; PS00227; TUBULIN; 1.
DR PROSITE; PS00228; TUBULIN_B_AUTOREG; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..447
FT /note="Tubulin beta-5 chain"
FT /id="PRO_0000048389"
FT BINDING 140..146
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000255"
SQ SEQUENCE 447 AA; 50309 MW; 4704AB7C6481A1F6 CRC64;
MREILHIQGG QCGNQIGSKF WEVVCDEHGI DPTGRYVGTS DLQLERVNVY YNEASCGRFV
PRAVLMDLEP GTMDSVRTGP YGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELIDSVLDVV
RKEAENCDCL QGFQVCHSLG GGTGSGMGTL LISKIREEYP DRMMLTFSVF PSPKVSDTVV
EPYNATLSVH QLVENADECM VLDNEALYDI CFRTLKLTTP SFGDLNHLIS ATMSGVTCCL
RFPGQLNSDL RKLAVNLIPF PRLHFFMVGF APLTSRGSQM YRSLTVPELT QQMWDSKNMM
CAADPRHGRY LTASAMFRGK MSTKEVDEQM INVQNKNSSY FVEWIPNNVK SSVCDIAPRG
LSMASTFIGN STSIQEMFRR VSEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVA
EYQQYQDATA DEEEELYEDE DDADLQE
