ID   TBC30_XENTR             Reviewed;         907 AA.
AC   Q28C33;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=TBC1 domain family member 30;
GN   Name=tbc1d30; ORFNames=TEgg107a03.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CR942478; CAJ81696.1; -; mRNA.
DR   RefSeq; NP_001039209.1; NM_001045744.1.
DR   AlphaFoldDB; Q28C33; -.
DR   SMR; Q28C33; -.
DR   STRING; 8364.ENSXETP00000012524; -.
DR   PaxDb; Q28C33; -.
DR   GeneID; 734068; -.
DR   KEGG; xtr:734068; -.
DR   CTD; 23329; -.
DR   Xenbase; XB-GENE-5823666; tbc1d30.
DR   eggNOG; KOG2058; Eukaryota.
DR   InParanoid; Q28C33; -.
DR   OrthoDB; 1162786at2759; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR   GO; GO:0090630; P:activation of GTPase activity; IBA:GO_Central.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   InterPro; IPR032738; Tbc1d30_C.
DR   Pfam; PF15733; DUF4682; 1.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 2.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..907
FT                   /note="TBC1 domain family member 30"
FT                   /id="PRO_0000320654"
FT   DOMAIN          243..451
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          51..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..781
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          812..859
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          872..907
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          583..645
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        761..777
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        820..850
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        873..907
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   907 AA;  101917 MW;  950F3EFE54803453 CRC64;
     MDVQAEDLFR DVESDAFVNE SHGGTGFQQN FSAWPGAFQV AWPLTNHQDL ASETQDNGNK
     SGGDEIDVSL CDSQQQGRSR TSSLVNGLLT ELYDTYRGGA GCYYFRQQDS VDSSTEASGS
     DAFLSRSNPE SGFLQELSER QSSRHQMLYL KQKDCSELKA IKDELNRRIA IQSAKLLRQV
     KQKDRLQHKV QKNCDIVTAC LQAVSQKRRV DTKLKFTLEP SLGQNGFQQW YDALKAVARL
     PTGIPKEWRK RVWLTLADHY LHSISIDWDK TMRFTFNDRS NPDDDSMGIQ IVKDLHRTGC
     SSYCGQEAEQ DRVVLKRVLL AYARWNKTIG YCQGFNILAA LILEVMEGNE GDALKVMIYL
     IDKVLPDSYF ANNLRALSVD MAVFRDLVRM KLPELSQHLD VLQRTANKES GGGYEPPLTN
     VFTMQWFLTL FATCLPNHTV LKIWDSVFFE GSEILLRVSL AIWAKLGEQI ECCQNSDDFY
     STMGRLTQEM LEDSLIDSNE LMQTVYSMAQ FPFPQLAELR EKYTYNITPF PAPVKSASFS
     GRTSKMRDSD EENEIDEDDV NANAVGCLGP FSGFLAPELQ KYQKQIKDQK EEQSLKASNI
     AELSPGAIDS CRSEYHAVFN SMMMERMTTD INALKQQYSR IKKRQLQQIN QVYIAADKGP
     VSCILPSQVN NSPVINHLLL GKKLKQVNRS KNALHLPASK SSLLANEETK AKQNSPWRTH
     IRVHRKNIAR AKGELGHGDT IGLIDEQNEV PKDQPDTSKE TEETAQPPCS SAGEETSLDR
     TVMKVDGRSP EPVYQDENAN VTVVQSKLEA LELSPDAETE VSLEMSQTFQ ESQSDSHSSS
     SESESFKKSP KVQVFSPFPS VKPLKKSATA RNLGLYGPNS RTPSVNFPHM SKTFNKAANG
     TTGSKKR